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Zinc Cluster

Known as: C6 Zinc Cluster 
The zinc cluster is one of three structural motifs observed in the DNA-binding domains of zinc proteins. In the "zinc cluster" two zinc atoms are… Expand
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
Enzyme-like chemoselective acylation of alcohols in the presence of amines catalyzed by a tetranuclear zinc cluster.
Acylation of alcohols and amines is one of the most fundamental reactions. Due to the greater nucleophilicity of the amino group… Expand
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Highly Cited
2006
Highly Cited
2006
Oxidative Stress-Activated Zinc Cluster Protein Stb5 Has Dual Activator/Repressor Functions Required for Pentose Phosphate Pathway Regulation and NADPH Production
ABSTRACT In Saccharomyces cerevisiae, zinc cluster protein Pdr1 can form homodimers as well as heterodimers with Pdr3 and Stb5… Expand
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Highly Cited
2005
Highly Cited
2005
Candida albicans Zinc Cluster Protein Upc2p Confers Resistance to Antifungal Drugs and Is an Activator of Ergosterol Biosynthetic Genes
ABSTRACT The human pathogen Candida albicans is responsible for a large proportion of infections in immunocompromised individuals… Expand
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Highly Cited
2005
Highly Cited
2005
An unprecedented eight-connected self-penetrating network based on pentanuclear zinc cluster building blocks.
The first eight-connected self-penetrating metal-organic framework, based on pentanuclear zinc cluster building blocks, defines a… Expand
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Highly Cited
2001
Highly Cited
2001
A Rsc3/Rsc30 zinc cluster dimer reveals novel roles for the chromatin remodeler RSC in gene expression and cell cycle control.
Chromatin remodeling complexes perform central roles in transcriptional regulation. Here, we identify Rsc3 and Rsc30 as novel… Expand
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Highly Cited
1998
Highly Cited
1998
Sequence-specific binding by Aspergillus nidulans AflR, a C6 zinc cluster protein regulating mycotoxin biosynthesis.
The Aspergillus nidulans aflR gene is found within a 60 kb gene cluster that includes approximately 24 other genes that… Expand
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Highly Cited
1996
Highly Cited
1996
Twenty-five coregulated transcripts define a sterigmatocystin gene cluster in Aspergillus nidulans.
Sterigmatocystin (ST) and the aflatoxins (AFs), related fungal secondary metabolites, are among the most toxic, mutagenic, and… Expand
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Highly Cited
1996
Highly Cited
1996
Comparative amino acid sequence analysis of the C6 zinc cluster family of transcriptional regulators.
The C6 zinc cluster family of fungal regulatory proteins shares as DNA-binding motif the C6 zinc cluster, also known as the Zn(II… Expand
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Highly Cited
1995
Highly Cited
1995
CAT8, a new zinc cluster-encoding gene necessary for derepression of gluconeogenic enzymes in the yeast Saccharomyces cerevisiae.
The expression of gluconeogenic fructose-1,6-bisphosphatase (encoded by the FBP1 gene) depends on the carbon source. Analysis of… Expand
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Highly Cited
1991
Highly Cited
1991
Zinc fingers, zinc clusters, and zinc twists in DNA-binding protein domains.
We now recognize three distinct motifs of DNA-binding zinc proteins: (i) zinc fingers, (ii) zinc clusters, and (iii) zinc twists… Expand
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