FAQ

Zinc Cluster

Known as: C6 Zinc Cluster 
The zinc cluster is one of three structural motifs observed in the DNA-binding domains of zinc proteins. In the "zinc cluster" two zinc atoms are… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
051019902018

Papers overview

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Highly Cited
2004
Highly Cited
2004
Transcriptional remodeling in response to iron deprivation in Saccharomyces cerevisiae.
The budding yeast Saccharomyces cerevisiae responds to depletion of iron in the environment by activating Aft1p, the major iron… (More)
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Highly Cited
2001
Highly Cited
2001
A Rsc3/Rsc30 zinc cluster dimer reveals novel roles for the chromatin remodeler RSC in gene expression and cell cycle control.
Chromatin remodeling complexes perform central roles in transcriptional regulation. Here, we identify Rsc3 and Rsc30 as novel… (More)
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2001
2001
Phenotypic analysis of genes encoding yeast zinc cluster proteins.
Zinc cluster proteins (or binuclear cluster proteins) possess zinc fingers of the Zn(II)2Cys6-type involved in DNA recognition as… (More)
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Highly Cited
1998
Highly Cited
1998
Sequence-specific binding by Aspergillus nidulans AflR, a C6 zinc cluster protein regulating mycotoxin biosynthesis.
The Aspergillus nidulans aflR gene is found within a 60 kb gene cluster that includes approximately 24 other genes that… (More)
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Highly Cited
1996
Highly Cited
1996
Comparative amino acid sequence analysis of the C6 zinc cluster family of transcriptional regulators.
The C6 zinc cluster family of fungal regulatory proteins shares as DNA-binding motif the C6 zinc cluster, also known as the Zn(II… (More)
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Highly Cited
1996
Highly Cited
1996
Twenty-five coregulated transcripts define a sterigmatocystin gene cluster in Aspergillus nidulans.
Sterigmatocystin (ST) and the aflatoxins (AFs), related fungal secondary metabolites, are among the most toxic, mutagenic, and… (More)
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Highly Cited
1996
Highly Cited
1996
Yeast SNF1 protein kinase interacts with SIP4, a C6 zinc cluster transcriptional activator: a new role for SNF1 in the glucose response.
The SNF1 protein kinase has been widely conserved in plants and mammals. In Saccharomyces cerevisiae, SNF1 is essential for… (More)
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Highly Cited
1995
Highly Cited
1995
CAT8, a new zinc cluster-encoding gene necessary for derepression of gluconeogenic enzymes in the yeast Saccharomyces cerevisiae.
The expression of gluconeogenic fructose-1,6-bisphosphatase (encoded by the FBP1 gene) depends on the carbon source. Analysis of… (More)
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Highly Cited
1993
Highly Cited
1993
Determinants of binding-site specificity among yeast C6 zinc cluster proteins.
Related DNA binding proteins often recognize similar DNA sites but can distinguish among them with the use of different protein… (More)
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Highly Cited
1991
Highly Cited
1991
Zinc fingers, zinc clusters, and zinc twists in DNA-binding protein domains.
We now recognize three distinct motifs of DNA-binding zinc proteins: (i) zinc fingers, (ii) zinc clusters, and (iii) zinc twists… (More)
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