• Publications
  • Influence
Atomic structure of the actin: DNase I complex
The atomic models of the complex between rabbit skeletal muscle actin and bovine pancreatic deoxyribonuclease I both in the ATP and ADP forms have been determined byo X-ray analysis at an effectiveExpand
  • 1,644
  • 95
  • PDF
X‐ray structure and activity of the yeast Pop2 protein: a nuclease subunit of the mRNA deadenylase complex
In Saccharomyces cerevisiae, a large complex, known as the Ccr4–Not complex, containing two nucleases, is responsible for mRNA deadenylation. One of these nucleases is called Pop2 and has beenExpand
  • 114
  • 18
Sequence‐dependent bending propensity of DNA as revealed by DNase I: parameters for trinucleotides.
Structural parameters characterizing the bending propensity of trinucleotides were deduced from DNase I digestion data using simple probabilistic models. In contrast to dinucleotide‐based models ofExpand
  • 273
  • 16
  • PDF
RNA binding in an Sm core domain: X‐ray structure and functional analysis of an archaeal Sm protein complex
Eukaryotic Sm and Sm‐like proteins associate with RNA to form the core domain of ribonucleoprotein particles involved in pre‐mRNA splicing and other processes. Recently, putative Sm proteins ofExpand
  • 157
  • 13
DNA recognition by DNase I
  • D. Suck
  • Biology, Medicine
  • Journal of molecular recognition : JMR
  • 1 June 1994
Bovine pancreatic DNase I shows a strong preference for double‐stranded substrates and cleaves DNA with strongly varying cutting rates suggesting that the enzyme recognises sequence‐dependentExpand
  • 106
  • 12
Sm-like proteins in Eubacteria: the crystal structure of the Hfq protein from Escherichia coli.
The Hfq protein was discovered in Escherichia coli in the early seventies as a host factor for the Qbeta phage RNA replication. During the last decade, it was shown to be involved in many RNAExpand
  • 194
  • 11
  • PDF
The crystal structure of an intact human Max-DNA complex: new insights into mechanisms of transcriptional control.
BACKGROUND Max belongs to the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. Max is able to form homodimers and heterodimers with other members of this family, whichExpand
  • 133
  • 11
Structure of southern bean mosaic virus at 2.8 Å resolution
X-ray diffraction studies reveal that the polypeptide chain of the southern bean mosaic virus protein subunit has a fold closely similar to the shell domain of tomato bushy stunt virus. TheExpand
  • 351
  • 10
Recognition of single‐stranded DNA by nuclease P1: High resolution crystal structures of complexes with substrate analogs
The reaction mechanism of nuclease P1 from Penicillium citrinum has been investigated using single‐stranded dithiophosphorylated di‐, tetra‐, and hexanucleotides as substrate analogs. The complexesExpand
  • 90
  • 9
Crystal structure of T4 endonuclease VII resolving a Holliday junction
Holliday proposed a four-way DNA junction as an intermediate in homologous recombination, and such Holliday junctions have since been identified as a central component in DNA recombination andExpand
  • 97
  • 9