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ZYX protein, human

Known as: Zyxin-2, HED-2 protein, human, ESP BE-20 protein, human 
Zyxin (572 aa, ~61 kDa) is encoded by the human ZYX gene. This protein is involved in focal adhesion assembly and function.
National Institutes of Health

Related topics

Related topics

15 relations
Cell AdhesionCell MovementCytokinesisCytoskeletal Gene

Broader (1)

Zyxin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction
Cells continuously sense and respond to external mechanical forces through their cytoskeleton. Here we show that only a small… 
Highly Cited
2012
Highly Cited
2012
Nanotopography as modulator of human mesenchymal stem cell function.
Review
2010
Review
2010
Biological activities of thymosin ß4 defined by active sites in short peptide sequences
Thymosin ß4, a small ubiquitous protein containing 43 aa, has structure/function activity via its actin‐binding domain and… 
Highly Cited
2006
Highly Cited
2006
Mechanical forces alter zyxin unbinding kinetics within focal adhesions of living cells
The formation of focal adhesions that mediate alterations of cell shape and movement is controlled by a mechanochemical mechanism… 
Highly Cited
2005
Highly Cited
2005
Cellular invasion by Staphylococcus aureus reveals a functional link between focal adhesion kinase and cortactin in integrin-mediated internalisation
Nosocomial infections by Staphylococcus aureus, a Gram-positive pathogen colonising human skin and mucosal surfaces, are an… 
Highly Cited
2005
Highly Cited
2005
The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration
Cell migration requires extension of lamellipodia that are stabilized by formation of adhesive complexes at the leading edge… 
Highly Cited
2004
Highly Cited
2004
Zyxin Interacts with the SH3 Domains of the Cytoskeletal Proteins LIM-nebulette and Lasp-1*
Zyxin is a versatile component of focal adhesions in eukaryotic cells. Here we describe a novel binding partner of zyxin, which… 
Highly Cited
2001
Highly Cited
2001
Targeting of Zyxin to Sites of Actin Membrane Interaction and to the Nucleus*
The localization of proteins to particular intracellular compartments often regulates their functions. Zyxin is a LIM protein… 
Highly Cited
2000
Highly Cited
2000
Directed Actin Polymerization Is the Driving Force for Epithelial Cell–Cell Adhesion
Highly Cited
1999
Highly Cited
1999
Inducible recruitment of Cdc42 or WASP to a cell-surface receptor triggers actin polymerization and filopodium formation
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