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Muricauda ruestringensis gen. nov., sp. nov., a facultatively anaerobic, appendaged bacterium from German North Sea intertidal sediment.
TLDR
Evidence based on phenotypic characteristics and 16S rDNA analysis supports the conclusion that this bacterium is distinct from its nearest relative, Zobellia uliginosa, and from the other genera of the Flavobacteriaceae. Expand
The multicellular morphotypes of Salmonella typhimurium and Escherichia coli produce cellulose as the second component of the extracellular matrix
TLDR
It is shown that, besides thin aggregative fimbriae, the second component of the extracellular matrix of the multicellular morphotype (rdar) of Salmonella typhimurium and Escherichia coli is cellulose. Expand
Pretreatment of Mice with Streptomycin Provides a Salmonella enterica Serovar Typhimurium Colitis Model That Allows Analysis of Both Pathogen and Host
TLDR
The results demonstrate that streptomycin-pretreated mice offer a unique infection model that allows for the first time to use mutants of both the pathogen and the host to study the molecular mechanisms of enteric salmonellosis. Expand
AgfD, the checkpoint of multicellular and aggregative behaviour in Salmonella typhimurium regulates at least two independent pathways
TLDR
It was concluded that agfD regulates at least two independent pathways contributing to the multicellular morphotype in S. typhimurium. Expand
Helicobacter exploits integrin for type IV secretion and kinase activation
TLDR
It is shown that the H. pylori CagL protein is a specialized adhesin that is targeted to the pilus surface, where it binds to and activates integrin α5β1 receptor on gastric epithelial cells through an arginine-glycine-aspartate motif. Expand
Identification of SopE2 from Salmonella typhimurium, a conserved guanine nucleotide exchange factor for Cdc42 of the host cell
TLDR
Transfection experiments showed that SopE2 is sufficient to activate host cellular CDC42, to recruit the actin‐nucleating Arp2/3 complex and to induce actin cytoskeletal rearrangements and internalization, and all S. typhimurium strains tested have the capacity to activate Cdc42 signalling inside host cells which is important to ensure efficient entry. Expand
α‐Enolase of Streptococcus pneumoniae is a plasmin(ogen)‐binding protein displayed on the bacterial cell surface
TLDR
A novel pneumococcal surface protein with a molecular mass of 47 kDa, designated Eno, which specifically binds human plasmin(ogen), exhibits α‐enolase activity and is necessary for viability is characterized. Expand
Illustration of Pneumococcal Polysaccharide Capsule during Adherence and Invasion of Epithelial Cells
TLDR
This study illustrates for the first time the phenotypic variation of the polysaccharide capsule in the initial phase of pneumococcal infections using a modified fixation method that allowed monitoring of the state of capsule expression of pathogens during the infectious process. Expand
Phagocytosis-independent antimicrobial activity of mast cells by means of extracellular trap formation.
TLDR
This study provides the first experimental evidence of antimicrobial extracellular traps formation by an immune cell population other than neutrophils, and takes advantage of the ability of MCs to kill the human pathogen Streptococcus pyogenes by a phagocytosis-independent mechanism. Expand
A novel sheathed surface organelle of the Helicobacter pylori cag type IV secretion system
TLDR
These observations demonstrate for the first time by microscopic techniques a complex T4SS‐associated, sheathed surface organelle reminiscent to the needle structures of bacterial type III secretion systems. Expand
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