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ZFP36 gene

Known as: ZFP36 ring finger protein, ZINC FINGER PROTEIN 36, MOUSE, HOMOLOG OF, ZFP36 
This gene plays a role in RNA turnover.
National Institutes of Health

Related topics

Related topics

6 relations
Ligand BindingRNA BindingRNA DegradationRNA Polyadenylation Regulation

Narrower (1)

ZFP36 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
A functional link between heme oxygenase-1 and tristetraprolin in the anti-inflammatory effects of nicotine.
2012
2012
ZFP36 expression impairs glioblastoma cell lines viability and invasiveness by targeting multiple signal transduction pathways
RNA binding proteins belonging to the TIS11/TTP gene family regulate the stability of multiple targets. Their inactivation or… 
2011
2011
Tristetraprolin Mediates Anti-inflammatory Effects of Nicotine in Lipopolysaccharide-stimulated Macrophages*
Nicotine inhibits the release of TNF-α from macrophage through activation of STAT3. Tristetraprolin (TTP) is known to destabilize… 
2011
2011
Novel Phosphorylation-dependent Ubiquitination of Tristetraprolin by Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase Kinase Kinase 1 (MEKK1) and Tumor Necrosis Factor Receptor…
Background: During inflammation, tristetraprolin displays a dual function as mRNA destabilizer and regulator of NF-κB signaling… 
2010
2010
Protein phosphatase 2A (PP2A) is increased in old murine B cells and mediates p38 MAPK/tristetraprolin dephosphorylation and E47 mRNA instability
Highly Cited
2009
Highly Cited
2009
RNA-destabilizing Factor Tristetraprolin Negatively Regulates NF-κB Signaling*
Tristetraprolin (TTP) is a CCCH zinc finger-containing protein that destabilizes mRNA by binding to an AU-rich element. Mice… 
2006
2006
Polysome-Bound Endonuclease PMR1 Is Targeted to Stress Granules via Stress-Specific Binding to TIA-1
ABSTRACT The generalized process of mRNA decay involves deadenylation followed by release from translating polysomes, decapping… 
Highly Cited
2004
Highly Cited
2004
The UL41 protein of herpes simplex virus mediates selective stabilization or degradation of cellular mRNAs
The UL41 protein of herpes simplex virus 1 has been reported to mediate the degradation of both viral and cellular mRNAs… 
2003
2003
Polymorphisms in the genes encoding members of the tristetraprolin family of human tandem CCCH zinc finger proteins.
2003
2003
Tristetraprolin binds to the COX-2 mRNA 3' untranslated region in cancer cells.
Consistent evidence of several types indicates that the inducible cyclooxygenase (COX-2) can promote the multi-step sequence of… 
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