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ZBTB16 gene

Known as: ZNF145, promyelocytic leukaemia zinc finger, Zinc Finger and BTB Domain Containing 16 Gene 
This gene plays a role in apoptosis and regulation of transcription. It is also involved in cell organization/biogenesis and megakaryocytic… 
National Institutes of Health

Related topics

Related topics

9 relations
Acute Promyelocytic LeukemiaMyelopoiesisTranscriptional RegulationTranscriptional Repression

Broader (1)

Genes

Narrower (1)

ZBTB16 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Promyelocytic Leukemia Zinc Finger Turns on the Effector T Cell Program without Requirement for Agonist TCR Signaling
Thymocytes expressing the NKT cell semi-invariant αβ TCR are thought to undergo agonist interactions with CD1d ligands prior to… 
Highly Cited
2009
Highly Cited
2009
Comprehensive genomic screens identify a role for PLZF-RARalpha as a positive regulator of cell proliferation via direct regulation of c-MYC.
The t(11;17)(q23;q21) translocation is associated with a retinoic acid (RA)-insensitive form of acute promyelocytic leukemia (APL… 
Highly Cited
2004
Highly Cited
2004
HDAC4 mediates transcriptional repression by the acute promyelocytic leukaemia-associated protein PLZF
PLZF, the promyelocytic leukaemia zinc-finger protein, is a transcriptional repressor essential to development. In some acute… 
Highly Cited
2002
Highly Cited
2002
The LIM-only Protein DRAL/FHL2 Interacts with and Is a Corepressor for the Promyelocytic Leukemia Zinc Finger Protein*
Members of the four-and-a-half-LIM domain (FHL) protein family, which are expressed in a tissue- and stage-specific manner, have… 
Review
2001
Review
2001
The role of promyelocytic leukemia zinc finger and promyelocytic leukemia in leukemogenesis and development
Acute promyelocytic leukemia (APL) was originally distinguished by an extremely poor clinical outcome. In the past few years… 
2000
2000
The aberrant fusion proteins PML-RARα and PLZF-RARα contribute to the overexpression of cyclin A1 in acute promyelocytic leukemia
Cyclin A1 is a newly discovered cyclin that is overexpressed in certain myeloid leukemias. Previously, the authors found that the… 
Highly Cited
1999
Highly Cited
1999
A novel BTB/POZ transcriptional repressor protein interacts with the Fanconi anemia group C protein and PLZF.
Fanconi anemia (FA) is an autosomal recessive cancer susceptibility syndrome. The phenotype includes developmental defects, bone… 
Highly Cited
1998
Highly Cited
1998
The Promyelocytic Leukemia Zinc Finger Protein Affects Myeloid Cell Growth, Differentiation, and Apoptosis
ABSTRACT The promyelocytic leukemia zinc finger (PLZF) gene, which is disrupted in therapy-resistant, t(11;17)(q23;q21… 
1997
1997
A high-resolution STS, EST, and gene-based physical map of the hereditary paraganglioma region on chromosome 11q23.
The genes responsible for hereditary paragangliomas (glomus tumors, MIM No. 168000) have been mapped to two distinct loci on the… 
Highly Cited
1995
Highly Cited
1995
Expression of the zinc-finger gene PLZF at rhombomere boundaries in the vertebrate hindbrain.
To investigate the potential biological role(s) of the PLZF gene, discovered as a fusion with the RARA locus in a patient with… 
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