Skip to search formSkip to main contentSkip to account menu

Z-360

A selective, orally available, 1,5-benzodiazepine-derivative gastrin/cholecystokinin 2 (CCK-2) receptor antagonist with potential antineoplastic… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Benzodiazepinones
NCIt Antineoplastic Agent Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
[99mTc]Tc-DGA1, a Promising CCK2R-Antagonist-Based Tracer for Tumor Diagnosis with SPECT.
Radiolabeled gastrin analogs have been proposed for theranostics of cholecystokinin subtype 2 receptor (CCK2R)-positive cancer… 
2017
2017
Z-360 Suppresses Tumor Growth in MIA PaCa-2-bearing Mice via Inhibition of Gastrin-induced Anti-Apoptotic Effects.
BACKGROUND/AIM The aim of the study was to evaluate the anti-tumor mechanism of Z-360, a gastrin/cholecystokinin-2 receptor… 
2016
2016
Abstract 3035: Development and characterization of CCK2R-targeted SMDCs and identification of GIST as a potential therapeutic indication
Cholecystokinin B receptor (CCKBR/CCK2R) is a GPCR of the cholecystokinin receptor family that is primarily expressed in the CNS… 
2010
2010
Pharmacological evaluation of analgesic effects of the cholecystokinin2 receptor antagonist Z-360 in mouse models of formalin- and cancer-induced pain.
Z-360, a novel cholecystokinin(2) (CCK(2)) receptor antagonist, has been developed as a therapeutic drug for pancreatic cancer… 
2010
2010
Efficacy of Z-360 on co-therapy with gemcitabine; Role of CCK2 receptor signaling on gemcitabine-induced VEGF expression
2008
2008
Gateways to clinical trials. July-August 2008.
(-)-Epigallocatechin gallate, 501516, 89-12; Abatacept, Adalimumab, Adefovir dipivoxil, AG-701, Agatolimod sodium, Alefacept… 
2003
2003
EFFECT OF Z-360, A SELECTIVE CCK_B/GASTRIN RECEPTOR ANTAGONIST, ON CHRONIC ACID REFLUX ESOPHAGITIS IN RATS
2002
2002
Z-360 の肝薬物代謝酵素に及ぼす影響 ―CYP2C 阻害を中心に―
2001
2001
Pharmacological profiles of Z-360, a novel CCKB/gastrin (CCK2) receptor antagonist with excellent oral potency
2001
2001
Effects of Z-360, a novel CCKB/gastrin (CCK2) receptor antagonist, on meal-induced acid secretion and experimental ulcer models in dogs and rats
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)