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Yeast One/Two-Hybrid System

Known as: Two Hybrid, Yeast One Hybrid System, Yeast Two Hybrid System 
Molecular biology technique used to identify interacting proteins in a yeast model. A protein of interest (the bait) is fused to the DNA-binding… 
National Institutes of Health

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Broader (1)

Genetic Techniques
Yeast Two-Hybrid System Techniquesexpression cloning

Papers overview

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Highly Cited
2011
Highly Cited
2011
Yeast Two Hybrid Analyses Reveal Novel Binary Interactions between Human Cytomegalovirus-Encoded Virion Proteins
Human cytomegalovirus (HCMV) is the largest human herpesvirus and its virion contains many viral encoded proteins found in the… 
Highly Cited
2010
Highly Cited
2010
Three-dimensional mineralization of dense nanofibrillar collagen-bioglass hybrid scaffolds.
Scaffolds for bone tissue engineering must meet a number of requirements such as biocompatibility, osteoconductivity… 
Highly Cited
2000
Highly Cited
2000
Indirect Reduction of Ear Molds and Associated Mycotoxins in Bacillus thuringiensis Corn Under Controlled and Open Field Conditions: Utility and Limitations
Abstract In 1995, ears of a experimental inbred (CG59-2) containing asynthetic Bacillus thuringiensis Cry IA(b) gene driven… 
Highly Cited
1999
Highly Cited
1999
NMR structure of the (52-96) C-terminal domain of the HIV-1 regulatory protein Vpr: molecular insights into its biological functions.
The HIV-1 regulatory protein Vpr (96 amino acid residues) is incorporated into the virus particle through a mechanism involving… 
Highly Cited
1996
Highly Cited
1996
Myosin heavy chain isoforms in adult equine skeletal muscle: An immunohistochemical and electrophoretic study
The aim of this study was to characterize the myosin heavy chain (MyHC) isoforms present in equine skeletal muscle. 
Review
1995
Review
1995
Mapping the Domains of Interaction of p40 with Both p47 and p67 of the Neutrophil Oxidase Complex Using the Two-hybrid System (*)
The superoxide-generating NADPH oxidase complex in phagocytic cells is constituted of a heterodimeric flavocytochrome b and… 
Highly Cited
1982
Highly Cited
1982
Maturation of the tail spike endorhamnosidase of Salmonella phage P22.
Highly Cited
1980
Highly Cited
1980
Monoclonal antibodies specific for carcinoembryonic antigen and produced by two hybrid cell lines.
Spleen cells from mice immunized with purified carcinoembryonic antigen (CEA), an important tumor marker of human carcinomas… 
Highly Cited
1979
Highly Cited
1979
Physical map of two D. melanogaster DNA segments containing sequences coding for the 70,000 dalton heat shock protein
Highly Cited
1978
Highly Cited
1978
Human α-globin gene expression following chromosomal dependent gene transfer into mouse erythroleukemia cells
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