Muscle architecture of the human lower limb.
- T. Wickiewicz, R. Roy, P. Powell, V. Edgerton
- BiologyClinical Orthopaedics and Related Research
- 1 October 1983
The architectural features of the major knee extensors and flexors and ankle plantarflexors and dorsiflexors were determined in three human cadavers and grouped according to whether they showed a predilection for tension or velocity of shortening.
Predictability of skeletal muscle tension from architectural determinations in guinea pig hindlimbs.
- P. Powell, R. Roy, P. Kanim, M. A. Bello, V. Edgerton
- BiologyJournal of applied physiology: respiratory…
- 1 December 1984
A specific tension value of 22.5 N X cm-2 appears to be a reasonable value for all mixed muscles studied in the guinea pig hindlimb and can be used to estimate their Po.
Recovery of supraspinal control of stepping via indirect propriospinal relay connections after spinal cord injury
It is shown that pronounced functional recovery can occur after severe SCI without the maintenance or regeneration of direct projections from the brain past the lesion and can be mediated by the reorganization of descending and propriospinal connections.
Effect of epidural stimulation of the lumbosacral spinal cord on voluntary movement, standing, and assisted stepping after motor complete paraplegia: a case study
HINDLIMB MUSCLE FIBER POPULATIONS OF FIVE MAMMALS
- M. Ariano, V. Edgerton, R. Armstrong
- BiologyJournal of Histochemistry and Cytochemistry
- 1 January 1973
It was found that the soleus and vastus intermedius muscles had the highest proportion of slow oxidative fibers in all five species, demonstrating the constancy of muscle fiber profiles dependent upon anatomical position and functional utilization.
Metabolic profiles of three fiber types of skeletal muscle in guinea pigs and rabbits.
Physiological cross‐sectional area of human leg muscles based on magnetic resonance imaging
The soleus fibers were unusually short relative to the muscle volume, thus potentiating its force potential, and these data illustrate some of the major limitations in the use of ACSA measurements to predict the functional properties of a muscle.
Specific tension of human plantar flexors and dorsiflexors.
The data suggest that factors other than PCSA contribute to the force output potential of ankle plantar flexors and dorsiflexors in humans.
Altering spinal cord excitability enables voluntary movements after chronic complete paralysis in humans.
- C. Angeli, V. Edgerton, Y. Gerasimenko, S. Harkema
- Medicine, BiologyBrain : a journal of neurology
- 1 May 2014
It is shown that neuromodulation of the sub-threshold motor state of excitability of the lumbosacral spinal networks was the key to recovery of intentional movement in four of four individuals diagnosed as having complete paralysis of the legs.
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input
It is proposed that, in the absence of supraspinal input, spinal locomotion can emerge from a combination of central pattern-generating capability and the ability of these spinal circuits to use sensory afferent input to control stepping.