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Xanthine Dehydrogenase

Known as: Xanthine Dehydrogenase [Chemical/Ingredient], Xanthine:NAD+ oxidoreductase, Xanthine Oxidoreductase 
An enzyme that catalyzes the oxidation of XANTHINE in the presence of NAD+ to form URIC ACID and NADH. It acts also on a variety of other purines and… 
National Institutes of Health

Related topics

Related topics

21 relations

Broader (2)

Alcohol OxidoreductasesKetone Oxidoreductases
Angiogenesis InhibitionCytoplasmic matrixEnzyme GeneIn Blood

Narrower (2)

Xanthinuria, Type IXanthinuria, Type II

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
A Monolithic and Self-Referenced RF LC Clock Generator Compliant With USB 2.0
A monolithic and self-referenced radio frequency (RF) LC clock generator that is compliant with USB 2.0 is demonstrated in a… 
Highly Cited
2003
Highly Cited
2003
Changing flux of xylose metabolites by altering expression of xylose reductase and xylitol dehydrogenase in recombinant Saccharomyces cerevisiae
We changed the fluxes of xylose metabolites in recombinant Saccharomyces cerevisiae by manipulating expression of Pichia stipitis… 
Highly Cited
2000
Highly Cited
2000
Influence of melatonin on free radical‐induced changes in rat pancreatic beta‐cells in vitro
Free radicals may produce cytotoxicity to pancreatic islets under pathophysiological conditions. The aim of our in vitro… 
Highly Cited
1997
Highly Cited
1997
Apoptosis of myelin-reactive T cells induced by reactive oxygen and nitrogen intermediates in vitro.
Apoptosis is a major mechanism of T cell elimination during ontogeny and tolerance induction as well as in autoimmunity. To… 
Highly Cited
1996
Highly Cited
1996
Reactive oxygen species block sperm-egg fusion via oxidation of sperm sulfhydryl proteins in mice.
The effects of reactive oxygen species (ROS) on mouse sperm-egg fusion were determined. Sperm were treated with superoxide and… 
Highly Cited
1990
Highly Cited
1990
Xanthine oxidoreductase activity in perfused hearts of various species, including humans.
Oxygen free radicals generated by xanthine oxidase have been implicated in cardiac damage. The activity of xanthine oxidase… 
Highly Cited
1990
Highly Cited
1990
Superoxide radical-mediated endothelial injury and vasoconstriction of rat thoracic aortic rings.
Endothelium regulates smooth muscle tone in response to various agonists and antagonists by release of vasorelaxing and… 
Highly Cited
1989
Highly Cited
1989
Xanthine oxidase-induced injury to endothelium: role of intracellular iron and hydroxyl radical.
The major objective of the present study was to characterize the sequence of events leading to endothelial cytotoxicity induced… 
Highly Cited
1983
Highly Cited
1983
Cellular and subcellular organization of pathways of ammonia assimilation and ureide synthesis in nodules of cowpea (Vigna unguiculata L. Walp.).
Highly Cited
1965
Highly Cited
1965
Electrophoretic variants of xanthine dehydrogenase in Drosophila melanogaster.
HE activity of xanthine dehydrogenase (XDH) in Drosophila melanogaster is affected by mutations at three loci: ma4 at locus 64ion… 
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