Xanthine Dehydrogenase

Known as: Xanthine Dehydrogenase [Chemical/Ingredient], Xanthine:NAD+ oxidoreductase, Xanthine Oxidoreductase 
An enzyme that catalyzes the oxidation of XANTHINE in the presence of NAD+ to form URIC ACID and NADH. It acts also on a variety of other purines and… (More)

Topic mentions per year

Topic mentions per year

1946-2017
0204019462016

Papers overview

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Highly Cited
2005
Highly Cited
2005
The purine analogue, allopurinol, has been in clinical use for more than 30 years as an inhibitor of xanthine oxidase (XO) in the… (More)
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Highly Cited
2004
Highly Cited
2004
We have performed a comparative study of xylose utilization in Saccharomyces cerevisiae transformants expressing two key enzymes… (More)
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Highly Cited
2003
Highly Cited
2003
Oscillatory shear stress occurs at sites of the circulation that are vulnerable to atherosclerosis. Because oxidative stress… (More)
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2001
2001
The enzyme xanthine oxidase (XO) has been implicated in the pathogenesis of several disease processes, such as ischemia… (More)
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Highly Cited
2000
Highly Cited
2000
Xanthine oxidase (XO) was shown to catalyze the reduction of nitrite to nitric oxide (NO), under anaerobic conditions, in the… (More)
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Highly Cited
2000
Highly Cited
2000
Mammalian xanthine oxidoreductases, which catalyze the last two steps in the formation of urate, are synthesized as the… (More)
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1997
1997
Xanthine dehydrogenase (XDH) and xanthine oxidase (XOD) are single-gene products that exist in separate but interconvertible… (More)
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Highly Cited
1989
Highly Cited
1989
The conversion of xanthine dehydrogenase to a free radical producing oxidase is an important component of oxygen-mediated tissue… (More)
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Highly Cited
1988
Highly Cited
1988
Oxygen radicals derived from xanthine oxidase (XO) are important mediators of the cellular injury associated with reperfusion of… (More)
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Highly Cited
1987
Highly Cited
1987
In response to global ischemia, tissue xanthine dehydrogenase was converted to xanthine oxidase in all tissues with half-times of… (More)
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