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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
There continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes, so it is important to update guidelines for monitoring autophagic activity in different organisms.
Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients
A specific marker of human PMN-MDSC associated with ER stress and lipid metabolism is identified, which provides new insights into the biology and potential therapeutic targeting of these cells.
Prevalence of Takotsubo cardiomyopathy in the United States.
Metabolic syndrome: pathophysiology, management, and modulation by natural compounds
- Y. Rochlani, N. Pothineni, S. Kovelamudi, J. Mehta
- Biology, MedicineTherapeutic advances in cardiovascular disease
- 22 June 2017
The epidemiology and pathogenesis of metabolic syndrome, the role of inflammation in MetS, and existing natural therapies for MetS are reviewed and summarized.
Prevalence of coronary artery disease in Asian Indians.
Lectin-like, oxidized low-density lipoprotein receptor-1 (LOX-1): a critical player in the development of atherosclerosis and related disorders.
Established and emerging plasma biomarkers in the prediction of first atherothrombotic events.
Although risk-scoring systems that additionally evaluate traditional risk factors such as smoking, hypertension, and diabetes greatly improve risk prediction, multiple studies demonstrate that 20% to 25% of all future events occur in individuals with only 1 of these factors.
Upregulation of endothelial receptor for oxidized LDL (LOX-1) by oxidized LDL and implications in apoptosis of human coronary artery endothelial cells: evidence from use of antisense LOX-1 mRNA and…
Findings indicate that ox-LDL upregulates its own endothelial receptor andmediated apoptosis of cultured human coronary artery endothelial cells (HCAECs) is mediated by the action of LOX-1.
Oxidized LDL, LOX-1 and Atherosclerosis
The role of ox-LDL and LOX-1 in genesis and progression of atherosclerosis is discussed, which promotes the growth and migration of smooth muscle cells, monocytes/macrophages and fibroblasts.
Malignant coronary artery disease in young asian indians: Thoughts on pathogenesis, prevention, and therapy
Aggressive modification of life style beginning before adolescence seems justified in view of the malignant nature of CAD in this population, and Pharmacologic intervention similar to that of secondary prevention of CAD seems justified as primary prevention in high‐risk Asian Indians.