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XRCC3 protein, human

Known as: DNA Repair Protein XRCC3, XRCC3, X-Ray Repair Cross-Complementing Protein 3 
DNA repair protein XRCC3 (346 aa, ~38 kDa) is encoded by the human XRCC3 gene. This protein is involved in homologous recombination repair of double… 
National Institutes of Health

Related topics

Related topics

12 relations
DNA RepairDNA Repair GeneDNA repair proteinDNA stability

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Polymorphisms in XPC, XPD, XRCC1, and XRCC3 DNA repair genes and lung cancer risk in a population of Northern Spain
BackgroundPolymorphisms in DNA repair genes have been associated to repair DNA lesions, and might contribute to the individual… 
Highly Cited
2006
Highly Cited
2006
Polymorphisms in DNA repair genes modulate survival in cisplatin/gemcitabine-treated non-small-cell lung cancer patients.
BACKGROUND Impaired DNA repair capacity may favorably affect survival in cisplatin/gemcitabine-treated non-small-cell lung cancer… 
Highly Cited
2004
Highly Cited
2004
Single nucleotide polymorphisms in breast cancer.
A limited number of genes have been identified that explain heritable risks of breast cancer (BC). We searched for low-penetrant… 
Highly Cited
2003
Highly Cited
2003
Polymorphisms in DNA repair and metabolic genes in bladder cancer.
We investigated the association of urinary bladder cancer with genetic polymorphisms in the xeroderma pigmentosum complementation… 
Highly Cited
2003
Highly Cited
2003
Polymorphisms of XRCC1 and XRCC3 genes and susceptibility to breast cancer.
Highly Cited
2002
Highly Cited
2002
Variants in DNA double-strand break repair genes and breast cancer susceptibility.
We performed genetic association studies in a population-based breast cancer case-control study analysing polymorphisms in genes… 
Highly Cited
2002
Highly Cited
2002
The genotype distribution of the XRCC1 gene indicates a role for base excision repair in the development of therapy-related acute myeloblastic leukemia.
Polymorphisms in several DNA repair genes have been described. These polymorphisms may affect DNA repair capacity and modulate… 
Highly Cited
2002
Highly Cited
2002
Defects in interstrand cross-link uncoupling do not account for the extreme sensitivity of ERCC1 and XPF cells to cisplatin.
The anticancer drug cisplatin reacts with DNA leading to the formation of interstrand and intrastrand cross-links that are the… 
Highly Cited
2001
Highly Cited
2001
DNA repair gene polymorphisms, bulky DNA adducts in white blood cells and bladder cancer in a case‐control study
Individuals differ widely in their ability to repair DNA damage, and DNA‐repair deficiency may be involved in modulating cancer… 
Highly Cited
2000
Highly Cited
2000
Evidence for Simultaneous Protein Interactions between Human Rad51 Paralogs*
In yeast, the Rad51-related proteins include Rad55 and Rad57, which form a heterodimer that interacts with Rad51. Five human… 
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