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XPC gene

Known as: RAD4, XPCC, Xeroderma Pigmentosum, Complementation Group C Gene 
This gene is involved in nucleotide excision repair.
National Institutes of Health

Related topics

Related topics

6 relations
DNA RepairDNA Repair Protein Complementing XP-C CellsNucleotide Excision RepairXERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP C

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XPC wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Single Nucleotide Polymorphisms in the NER Pathway and Clinical Outcome of Patients with Bone Malignant Tumor
The effects of polymorphisms in ERCC5, ERCC6, XPC, CCNH and MMS19L on osteosarcoma response to chemotherapy and the survival of… 
2008
2008
Polymorphisms of the DNA Repair Gene XPA and XPC and its Correlation With Gastric Cardiac Adenocarcinoma in a High Incidence Population in North China
Goals Investigated the association of DNA repair gene xeroderma pigmentosum group A(XPA) and C(XPC) polymorphisms with the risk… 
Highly Cited
2007
Highly Cited
2007
XPA A23G, XPC Lys939Gln, XPD Lys751Gln and XPD Asp312Asn polymorphisms, interactions with smoking, alcohol and dietary factors, and risk of colorectal cancer.
Highly Cited
2007
Highly Cited
2007
Long-term XPC silencing reduces DNA double-strand break repair.
To study the relationships between different DNA repair pathways, we established a set of clones in which one specific DNA repair… 
2005
2005
The Rad4 homologue YDR314C is essential for strand‐specific repair of RNA polymerase I‐transcribed rDNA in Saccharomyces cerevisiae
The Saccharomyces cerevisiae protein Rad4 is involved in damage recognition in nucleotide excision repair (NER). In RNA… 
Highly Cited
2003
Highly Cited
2003
Tumor suppressor p53 dependent recruitment of nucleotide excision repair factors XPC and TFIIH to DNA damage.
Highly Cited
2002
Highly Cited
2002
Proteolysis of a nucleotide excision repair protein by the 26S proteasome
The 26S proteasome degrades a broad spectrum of proteins and interacts with several nucleotide excision repair (NER) proteins… 
Highly Cited
2000
Highly Cited
2000
Ultraviolet B radiation-induced skin cancer in mice defective in the Xpc, Trp53, and Apex (HAP1) genes: genotype-specific effects on cancer predisposition and pathology of tumors.
Mutations in nucleotide excision repair (NER) genes in humans result in the UV-induced skin cancer-prone disease xeroderma… 
1988
1988
Cloning and nucleotide sequence analysis of the Saccharomyces cerevisiae RAD4 gene required for excision repair of UV-damaged DNA.
1987
1987
RAD4 gene of Saccharomyces cerevisiae: molecular cloning and partial characterization of a gene that is inactivated in Escherichia coli
In contrast to other Saccharomyces cerevisiae RAD genes involved in nucleotide excision repair of DNA, the RAD4 gene could not be… 
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