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XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP C

Known as: XERODERMA PIGMENTOSUM III, XPCC, XP, Group C 
An autosomal recessive inherited disorder caused by mutations in the XPC gene. This disease is characterized by increased sensitivity to sunlight… Expand
National Institutes of Health

Papers overview

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Review
2013
Review
2013
SIGNIFICANCE Oxidative DNA damage is repaired by multiple, overlapping DNA repair pathways. Accumulating evidence supports the… Expand
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2010
2010
Xeroderma pigmentosum (XP) is a rare autosomal recessive disorder that is associated with an inherited defect of the nucleotide… Expand
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2009
2009
Xeroderma pigmentosum group C (XPC) protein initiates the DNA excision repair of helix-distorting base lesions. To understand how… Expand
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2008
2008
The accumulation of DNA damage is a slow but hazardous phenomenon that may lead to cell death, accelerated aging, and cancer. One… Expand
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2007
2007
The Xeroderma Pigmentosum group C (XPC) protein is indispensable to global genomic repair (GGR), a subpathway of nucleotide… Expand
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Highly Cited
2005
Highly Cited
2005
Xeroderma pigmentosum group C (XPC) protein plays a key role in DNA damage recognition in global genome nucleotide excision… Expand
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Highly Cited
2005
Highly Cited
2005
The xeroderma pigmentosum group C (XPC) protein complex plays a key role in recognizing DNA damage throughout the genome for… Expand
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Highly Cited
2003
Highly Cited
2003
Primary DNA damage sensing in mammalian global genome nucleotide excision repair (GG-NER) is performed by the xeroderma… Expand
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Highly Cited
2002
Highly Cited
2002
The p53 tumor suppressor gene product is a transcription factor involved in cell-cycle regulation, apoptosis, and DNA repair. We… Expand
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Highly Cited
1998
Highly Cited
1998
The XPC-HR23B complex is specifically involved in global genome but not transcription-coupled nucleotide excision repair (NER… Expand
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