XPC, IVS3AS, T-A, -9
National Institutes of Health
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Several studies have evaluated the relationship between xeroderma pigmentosum complementation group C (XPC) variants and prostate…
Polymorphisms of the XPC gene have been reported to be associated with an increased risk of head and neck cancer (HNC), though…
One of the most versatile mammalian DNA repair pathways is nucleotide excision repair (NER) in which repair factors assemble…
Prostate cancer is a common disease with a multifactorial and complex etiology. It is the most common male malignancy and the…
Objective and Methods In order to clarify the association between the two polymorphisms:Ala499Val and Lys939Gln in XPC in NER…
Xeroderma pigmentousum group C protein (XPC) is involved in the first step of nucleotide excision repair, with multiple…
已知 DNA 修補能力 (DRC) 降低與肺癌形成有關，尤其是不抽菸者。XPC是第一個認知 DNA 傷害之 nucleotide excision repair 的蛋白。動物模式研究發現剔除 XPC 基因之小鼠會造成肺腺癌之形成。又知 p53 可做為 XPC…
The rationale behind gene-disease association studies is that genetic variants (polymorphisms) result in alterations in…
It has been reported that 80–90% of human cancers may result, in part, from DNA damage. Cell survival depends critically on the…