XIAP gene

Known as: XIAP, INHIBITOR OF APOPTOSIS, X-LINKED, X-Linked Inhibitor of Apoptosis Gene 
This gene is involved in apoptotic regulation through caspase interaction.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
FAS (also called APO-1 and CD95) and its physiological ligand, FASL, regulate apoptosis of unwanted or dangerous cells… (More)
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Highly Cited
2006
Highly Cited
2006
The homeostasis of the immune response requires tight regulation of the proliferation and apoptosis of activated lymphocytes. In… (More)
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Highly Cited
2003
Highly Cited
2003
The inhibitor of apoptosis (IAP) proteins potently inhibit the catalytic activity of caspases. While profound insight into the… (More)
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Highly Cited
2001
Highly Cited
2001
X-linked inhibitor-of-apoptosis protein (XIAP) interacts with caspase-9 and inhibits its activity, whereas Smac (also known as… (More)
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Highly Cited
2001
Highly Cited
2001
X chromosome-linked inhibitor of apoptosis (XIAP) is an endogenous inhibitor of caspase-3, -7, and -9. Smac/DIABLO, an inhibitor… (More)
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Highly Cited
2001
Highly Cited
2001
The inhibitor of apoptosis protein (IAP) family consists of a number of evolutionarily conserved proteins that function to… (More)
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Highly Cited
2001
Highly Cited
2001
The molecular mechanism(s) that regulate apoptosis by caspase inhibition remain poorly understood. The main endogenous inhibitors… (More)
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Review
2001
Review
2001
The X-linked Inhibitor of Apoptosis, XIAP, is a key member of the newly discovered family of intrinsic inhibitors of apoptosis… (More)
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Highly Cited
1999
Highly Cited
1999
Several human inhibitor of apoptosis (IAP) family proteins function by directly inhibiting specific caspases in a mechanism that… (More)
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Highly Cited
1998
Highly Cited
1998
The inhibitor of apoptosis proteins (IAPs) constitute an evolutionarily conserved family of homologous proteins that suppress… (More)
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