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XIAP gene

Known as: XIAP, INHIBITOR OF APOPTOSIS, X-LINKED, X-Linked Inhibitor of Apoptosis Gene 
This gene is involved in apoptotic regulation through caspase interaction.
National Institutes of Health

Related topics

Related topics

4 relations
ApoptosisBIRC4 protein, humanNegative Regulation of Apoptosis

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XIAP wt Allele

Papers overview

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Highly Cited
2004
Highly Cited
2004
Roscovitine sensitizes glioma cells to TRAIL-mediated apoptosis by downregulation of survivin and XIAP
The cytotoxic effect of the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is limited in many glioma cell lines… 
Highly Cited
2004
Highly Cited
2004
X-linked inhibitor of apoptosis (XIAP) confers human trophoblast cell resistance to Fas-mediated apoptosis.
Apoptosis occurs in the placenta throughout gestation, with a greater frequency near term in comparison to the first trimester… 
Highly Cited
2003
Highly Cited
2003
Proteasome Inhibition Results in TRAIL Sensitization of Primary Keratinocytes by Removing the Resistance-Mediating Block of Effector Caspase Maturation
ABSTRACT Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) exerts potent cytotoxic activity against transformed… 
Highly Cited
2003
Highly Cited
2003
Low Power 0 / 1 Coverage and Scheduling Techniques in Sensor Networks
Distributed embedded systems have recently emerged as an economically attractive and technically challenging research direction… 
Highly Cited
2002
Highly Cited
2002
Resistance to Fas-mediated apoptosis in human lung fibroblast
The current authors have demonstrated previously that epithelial cell apoptosis, induced by the Fas-Fas ligand pathway, might be… 
Highly Cited
2002
Highly Cited
2002
XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis
Ligation of death receptors or formation of the Apaf-1 apoptosome results in the activation of caspases and execution of… 
Highly Cited
2001
Highly Cited
2001
Direct inhibition of caspase 3 is dispensable for the anti‐apoptotic activity of XIAP
XIAP is a mammalian inhibitor of apoptosis protein (IAP). To determine residues within the second baculoviral IAP repeat (BIR2… 
Highly Cited
2000
Highly Cited
2000
TNF- α augments intratumoural concentrations of doxorubicin in TNF- α -based isolated limb perfusion in rat sarcoma models and enhances anti-tumour effects
We have shown previously that isolated limb perfusion (ILP) in sarcoma-bearing rats results in high response rates when melphalan… 
Highly Cited
2000
Highly Cited
2000
XIAP Regulates DNA Damage-induced Apoptosis Downstream of Caspase-9 Cleavage*
The IAP (inhibitor ofapoptosis) family of anti-apoptotic proteins regulates programmed cell death. Of the six known human IAP… 
Highly Cited
1993
Highly Cited
1993
Local treatment of colorectal liver metastases: a comparison of interstitial laser photocoagulation (ILP) and percutaneous alcohol injection (PAI).
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