Wnt Signaling Pathway

Known as: Pathways, Wnt, Wnt receptor signaling pathway, Wingless signalling pathway 
A complex signaling pathway whose name is derived from the DROSOPHILA Wg gene, which when mutated results in the wingless phenotype, and the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1987-2017
05019872017

Papers overview

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Highly Cited
2011
Highly Cited
2011
Misregulated β-catenin responsive transcription (CRT) has been implicated in the genesis of various malignancies, including… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND The Wnt signaling pathway plays key roles in development, adult tissue homeostasis and stem cell maintenance. Further… (More)
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Highly Cited
2005
Highly Cited
2005
  • Ramanuj DasGupta, Ajamete Kaykas, Randall T. Moon, Norbert Perrimon
  • Science
  • 2005
The Wnt-Wingless (Wg) pathway is one of a core set of evolutionarily conserved signaling pathways that regulates many aspects of… (More)
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Highly Cited
2003
Highly Cited
2003
Breast cancer is a genetically and clinically heterogeneous disease, and the contributions of different target cells and… (More)
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Highly Cited
2001
Highly Cited
2001
Primitive neuroectodermal tumors (PNETs) represent the most frequent malignant brain tumors in childhood. The majority of these… (More)
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Highly Cited
2001
Highly Cited
2001
Accumulation of beta-catenin in cytoplasm and nuclei is frequently observed in a wide variety of tumors arising, for example, in… (More)
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Highly Cited
2001
Highly Cited
2001
NEDD8/Rub1 is a ubiquitin (Ub)-like molecule that covalently ligates to target proteins through an enzymatic cascade analogous to… (More)
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Highly Cited
2000
Highly Cited
2000
The transforming growth factor-beta (TGFbeta) and Wnt/wingless pathways play pivotal roles in tissue specification during… (More)
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Highly Cited
1997
Highly Cited
1997
Glycogen synthase kinase-3 beta (GSK-3 beta/zeste-white-3/shaggy) is a negative regulator of the wnt signaling pathway which… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Wnts are secreted proteins implicated in cell-cell interactions during embryogenesis and tumorigenesis, but receptors… (More)
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