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Wnt Signaling Pathway

Known as: Pathways, Wnt, Wnt receptor signaling pathway, Wingless signalling pathway 
A complex signaling pathway whose name is derived from the DROSOPHILA Wg gene, which when mutated results in the wingless phenotype, and the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Background The Wnt signaling pathway plays key roles in development, adult tissue homeostasis and stem cell maintenance. Further… Expand
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Review
2006
Review
2006
The signaling pathway mediated by Wingless-type (Wnt) proteins is highly conserved in evolution. This pivotal pathway is known to… Expand
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Highly Cited
2005
Highly Cited
2005
The Wnt-Wingless (Wg) pathway is one of a core set of evolutionarily conserved signaling pathways that regulates many aspects of… Expand
Highly Cited
2003
Highly Cited
2003
Breast cancer is a genetically and clinically heterogeneous disease, and the contributions of different target cells and… Expand
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Highly Cited
2001
Highly Cited
2001
Accumulation of beta-catenin in cytoplasm and nuclei is frequently observed in a wide variety of tumors arising, for example, in… Expand
Review
2000
Review
2000
Members of the vertebrate Wnt family have been subdivided into two functional classes according to their biological activities… Expand
Highly Cited
2000
Highly Cited
2000
The transforming growth factor-beta (TGFbeta) and Wnt/wingless pathways play pivotal roles in tissue specification during… Expand
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Highly Cited
1997
Highly Cited
1997
Glycogen synthase kinase-3 beta (GSK-3 beta/zeste-white-3/shaggy) is a negative regulator of the wnt signaling pathway which… Expand
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Highly Cited
1997
Highly Cited
1997
wingless and decapentaplegic signal during endoderm induction in Drosophila to regulate expression of the homeotic gene… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Wnts are secreted proteins implicated in cell-cell interactions during embryogenesis and tumorigenesis, but receptors… Expand