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AXIN1 wt Allele

Known as: Axin 1 wt Allele, MGC52315, Fused, Mouse, Homolog of Gene 
Human AXIN1 wild-type allele is located in the vicinity of 16p13.3 and is approximately 65 kb in length. This allele, which encodes axin-1 protein… 
National Institutes of Health

Related topics

Related topics

13 relations
16p13.3ALK PathwayAXIN1 proteinBeta-Catenin Accumulation Pathway

Broader (1)

AXIN1 gene

Papers overview

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2016
2016
Dual Roles for Membrane Association of Drosophila Axin in Wnt Signaling
Deregulation of the Wnt signal transduction pathway underlies numerous congenital disorders and cancers. Axin, a concentration… 
2014
2014
The Drosophila tankyrase regulates Wg signaling depending on the concentration of Daxin.
2013
2013
Expression and localization of axin 2 in colorectal carcinoma and its clinical implication
PurposeAberrant activation of the Wnt/β-catenin pathway plays a major role in the development of colorectal carcinoma (CRC). Axin… 
2012
2012
Differential Role of Axin RGS Domain Function in Wnt Signaling during Anteroposterior Patterning and Maternal Axis Formation
Axin is a critical component of the β-catenin destruction complex and is also necessary for Wnt signaling initiation at the level… 
2011
2011
Stem Cells , Tissue Engineering , and Hematopoietic Elements-Catenin Dosage Is a Critical Determinant of Tracheal Basal Cell Fate Determination
The purpose of this study was to determine whether -catenin regulates basal cell fate determination in the mouse trachea… 
2009
2009
Changes of AXIN-1 and Beta-Catenin in Neuroepithelial Brain Tumors
In the present study changes of components of Wnt signaling pathway—axin (AXIN1) and beta-catenin (CTNNB1) in a sample of 72… 
2009
2009
Membrane Bound Axin Is Sufficient for Wingless Signaling in Drosophila Embryos
The Wingless signaling pathway controls various developmental processes in both vertebrates and invertebrates. Here I probe the… 
Highly Cited
2008
Highly Cited
2008
The inhibitory effects of Disabled-2 (Dab2) on Wnt signaling are mediated through Axin
β-Catenin-mediated Wnt signaling is essential in embryonic development and in adult tissues. Recent studies have demonstrated… 
Highly Cited
2001
Highly Cited
2001
The role of maternal axin in patterning the Xenopus embryo.
Regulation of the stability of beta catenin protein is a critical role of Wnt signaling cascades. In early Xenopus development… 
1999
1999
Radiation hybrid mapping of genes in the lithium-sensitive Wnt signaling pathway
Lithium, an effective drug in the treatment of bipolar disorder, has been proposed to disrupt the Wnt signaling pathway. To… 
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