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AXIN1 gene

Known as: Axin 1 Gene, AXIS INHIBITOR 1, FUSED, MOUSE, HOMOLOG OF 
This gene plays a role in signal transduction and is involved in development.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
SUMMARY The pervasive influence of secreted Wnt signaling proteins in tissue homeostasis and tumorigenesis has galvanized efforts… Expand
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Highly Cited
2003
Highly Cited
2003
Wnt signaling plays an important role in both oncogenesis and development. Activation of the Wnt pathway results in stabilization… Expand
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Highly Cited
2002
Highly Cited
2002
Activation of Wnt signaling through β-catenin mutations contributes to the development of hepatocellular carcinoma (HCC) and… Expand
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Highly Cited
2001
Highly Cited
2001
To understand how the Wnt coreceptor LRP-5 is involved in transducing the canonical Wnt signals, we identified Axin as a protein… Expand
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Highly Cited
2000
Highly Cited
2000
The Wnt signalling pathway is essential for development and organogenesis. Wnt signalling stabilizes β-catenin, which accumulates… Expand
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Highly Cited
2000
Highly Cited
2000
The adenomatous polpyposis coli (APC) protein is mutated in most colorectal tumours. Nearly all APC mutations are truncations… Expand
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Highly Cited
1999
Highly Cited
1999
ABSTRACT The N-terminal region of Dvl-1 (a mammalian Dishevelled homolog) shares 37% identity with the C-terminal region of Axin… Expand
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Highly Cited
1998
Highly Cited
1998
Glycogen synthase kinase‐3 (GSK‐3) mediates epidermal growth factor, insulin and Wnt signals to various downstream events such as… Expand
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Highly Cited
1998
Highly Cited
1998
Abstract Background: Inactivation of the adenomatous polyposis coli (APC) tumor suppressor protein is responsible for both… Expand
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Highly Cited
1997
Highly Cited
1997
Mutations at the mouse Fused locus have pleiotropic developmental effects, including the formation of axial duplications in… Expand
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