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Wnt Inhibitory Factor 1
Known as:
WIF-1
, WIF1
Wnt inhibitory factor 1 (379 aa, ~42 kDa) is encoded by the human WIF1 gene. This protein plays a role in the negative regulation of Wnt signaling.
National Institutes of Health
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Related topics
Related topics
13 relations
Beta-Catenin Accumulation Pathway
EGF-Like Domain
Extracellular Space
Pitx2 Transcription Regulation Pathway
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Curcumin-loaded nanoparticles potently induce adult neurogenesis and reverse cognitive deficits in Alzheimer's disease model via canonical Wnt/β-catenin pathway.
S. Tiwari
,
S. Agarwal
,
+13 authors
K. Gupta
ACS Nano
2014
Corpus ID: 21037973
Neurogenesis, a process of generation of new neurons, is reported to be reduced in several neurodegenerative disorders including…
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Highly Cited
2014
Highly Cited
2014
MicroRNA-181a promotes tumor growth and liver metastasis in colorectal cancer by targeting the tumor suppressor WIF-1
D. Ji
,
Zhiguo Chen
,
+6 authors
J. Gu
Molecular Cancer
2014
Corpus ID: 8675864
BackgroundGiven the emerging role of microRNA in tumor disease progression, we investigated the association between microRNA…
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Highly Cited
2013
Highly Cited
2013
HOTAIR, a prognostic factor in esophageal squamous cell carcinoma, inhibits WIF‐1 expression and activates Wnt pathway
Xiao-song Ge
,
Hua Ma
,
+6 authors
W. Jia
Cancer Science
2013
Corpus ID: 12517867
Long non‐coding RNAs (LncRNAs) have been recently found to be pervasively transcribed in the genome and critical regulators of…
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Highly Cited
2010
Highly Cited
2010
Transcriptional Profiles Predict Disease Outcome in Patients with Cutaneous T-Cell Lymphoma
I. Litvinov
,
David A Jones
,
D. Sasseville
,
T. Kupper
Clinical Cancer Research
2010
Corpus ID: 15028180
Purpose: Average survival of cutaneous T-cell lymphoma (CTCL) is associated with clinical stage at diagnosis, where stage I has a…
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Highly Cited
2009
Highly Cited
2009
Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice.
M. Kansara
,
M. Tsang
,
+9 authors
David M. Thomas
Journal of Clinical Investigation
2009
Corpus ID: 24363204
Wnt signaling increases bone mass by stimulating osteoblast lineage commitment and expansion and forms the basis for novel…
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Highly Cited
2009
Highly Cited
2009
Aberrant Methylation of APC, MGMT, RASSF2A, and Wif-1 Genes in Plasma as a Biomarker for Early Detection of Colorectal Cancer
B. Lee
,
Eun Ju Lee
,
+5 authors
Duk-Hwan Kim
Clinical Cancer Research
2009
Corpus ID: 16402274
Purpose: To identify epigenetic molecular makers in plasma for the early detection of colorectal cancer. Experimental Design: We…
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Highly Cited
2008
Highly Cited
2008
CpG island hypermethylation of E‐cadherin (CDH1) and integrin α4 is associated with recurrence of early stage esophageal squamous cell carcinoma
Eunju Lee
,
B. Lee
,
+4 authors
Duk-Hwan Kim
International Journal of Cancer
2008
Corpus ID: 20711891
The prognosis of esophageal squamous cell carcinoma (ESCC) patients remains very poor, which is partially due to a high rate of…
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Highly Cited
2007
Highly Cited
2007
Unravelling the molecular control of calvarial suture fusion in children with craniosynostosis
A. Coussens
,
C. R. Wilkinson
,
+4 authors
B. Powell
BMC Genomics
2007
Corpus ID: 456871
BackgroundCraniosynostosis, the premature fusion of calvarial sutures, is a common craniofacial abnormality. Causative mutations…
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Highly Cited
2007
Highly Cited
2007
Combination analysis of hypermethylated Wnt-antagonist family genes as a novel epigenetic biomarker panel for bladder cancer detection.
S. Urakami
,
H. Shiina
,
+8 authors
R. Dahiya
Clinical Cancer Research
2007
Corpus ID: 16906733
Review
2005
Review
2005
Wnt signaling in lung cancer.
J. Mazières
,
B. He
,
L. You
,
Zhidong Xu
,
D. Jablons
Cancer Letters
2005
Corpus ID: 22410101
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