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WY 14,643

Known as: Wy-14643, Wyeth-14643, WY14,643 
 
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
Plasma FGF21 levels and hepatic FGF21 gene expression increase dramatically after birth in mice. This induction is initiated by… Expand
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Highly Cited
2005
Highly Cited
2005
Palmitoylethanolamide (PEA), the naturally occurring amide of palmitic acid and ethanolamine, reduces pain and inflammation… Expand
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Highly Cited
2004
Highly Cited
2004
Administration of a methionine and choline deficient (MCD) diet to rodents causes progressive fibrosing steatohepatitis… Expand
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Highly Cited
2002
Highly Cited
2002
Peroxisome proliferator activated receptors (PPARs) are ligand-activated transcription factors with diverse actions including… Expand
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Highly Cited
1997
Highly Cited
1997
Chronic administration of peroxisome proliferators to mice and rats results in hepatomegaly and ultimately carcinogenesis. The… Expand
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Highly Cited
1995
Highly Cited
1995
To gain insight into the function of peroxisome proliferator-activated receptor (PPAR) isoforms in rodents, we disrupted the… Expand
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Highly Cited
1995
Highly Cited
1995
In view of the evidence linking plasma high density lipoprotein (HDL)-cholesterol levels to a protective effect against coronary… Expand
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Highly Cited
1992
Highly Cited
1992
Peroxisome proliferators such as clofibric acid, nafenopin, and WY-14,643 have been shown to activate PPAR (peroxisome… Expand
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Highly Cited
1988
Highly Cited
1988
The mechanism of hepatocarcinogenesis caused by peroxisome proliferators (PP) is poorly understood, making it difficult to… Expand
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Highly Cited
1980
Highly Cited
1980
Several drugs, including clofibrate (ethyl-a-p-chlorophenoxyisobutyrate)1, are now available for the treatment of… Expand
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