Skip to search formSkip to main contentSkip to account menu

WY 14,643

Known as: Wy-14643, Wyeth-14643, WY14,643 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

pirinixic acid

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2001
Highly Cited
2001
Polyunsaturated fatty acids stimulate hepatic UCP-2 expression via a PPARα-mediated pathway
The discovery of homologs of the brown fat uncoupling protein(s) (UCP) UCP-2 and UCP-3 revived the hypothesis of uncoupling… 
Highly Cited
2000
Highly Cited
2000
Differential effects of PPARalpha activators on induction of ectopic expression of tissue-specific fatty acid binding protein genes in the mouse liver.
Highly Cited
1996
Highly Cited
1996
The effects of peroxisome proliferators on protein abundances in mouse liver.
We have investigated the effects of five peroxisome proliferators (PPs : clofibric acid, DEHP, WY14,643, nafenopin, and LY171883… 
Highly Cited
1989
Highly Cited
1989
Relationship of oxidative damage to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and Wy-14,643.
Quantitative comparisons of the time course of biochemical and morphological changes induced by peroxisome proliferators… 
Highly Cited
1989
Highly Cited
1989
Differential induction and regulation of peroxisomal enzymes: predictive value of peroxisome proliferation in identifying certain nonmutagenic carcinogens.
Highly Cited
1988
Highly Cited
1988
Tissue specificity and species differences in the distribution of urate oxidase in peroxisomes.
The localization of urate oxidase in different tissues of rat and in the livers of selected mammalian species was investigated by… 
Highly Cited
1985
Highly Cited
1985
32P-postlabeling analysis of peroxisome proliferator-DNA adduct formation in rat liver in vivo and hepatocytes in vitro.
Hepatocarcinogenic peroxisome proliferators, clofibrate, ciprofibrate, Wy-14643 or di(2-ethylhexyl)phthalate, were administered… 
Highly Cited
1984
Highly Cited
1984
Effect of hypolipidemic peroxisome proliferators on unscheduled DNA synthesis in cultured hepatocytes and on mutagenesis in Salmonella.
Highly Cited
1983
Highly Cited
1983
Peroxisome proliferation in primary cultures of rat hepatocytes.
Highly Cited
1982
Highly Cited
1982
The absence of gamma-glutamyl transpeptidase activity in putative preneoplastic lesions and in hepatocellular carcinomas induced in rats by the hypolipidemic peroxisome proliferator Wy-14,643.
Administration of Wy-14,643, a hypolipidemic agent which induces peroxisome proliferation, at a concentration of 0.1% (w/w) in… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)