WY 14,643

Known as: Wy-14643, Wyeth-14643, WY14,643 
 
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Peroxisome proliferators, such as lipid-lowering fibrate drugs, are agonists for the peroxisome proliferator-activated receptor… (More)
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Highly Cited
2006
Highly Cited
2006
Severe pain remains a major area of unmet medical need. Here we report that agonists of the nuclear receptor PPAR-alpha… (More)
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Highly Cited
2004
Highly Cited
2004
Administration of a methionine and choline deficient (MCD) diet to rodents causes progressive fibrosing steatohepatitis… (More)
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Highly Cited
1997
Highly Cited
1997
Chronic administration of peroxisome proliferators to mice and rats results in hepatomegaly and ultimately carcinogenesis. The… (More)
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1997
1997
Peroxisome proliferators are a group of nongenotoxic carcinogens which include a number of hypolipidemic drugs, solvents, and… (More)
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Highly Cited
1995
Highly Cited
1995
To gain insight into the function of peroxisome proliferator-activated receptor (PPAR) isoforms in rodents, we disrupted the… (More)
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1994
1994
The biological potential of hepatic foci and tumors induced by peroxisome proliferators such as Wy-14,643 has been poorly… (More)
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1991
1991
The carcinogenicity of the peroxisome proliferator WY-14,643 was compared in young (starting age 2 months) and old (starting age… (More)
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1989
1989
Quantitative comparisons of the time course of biochemical and morphological changes induced by peroxisome proliferators… (More)
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Highly Cited
1988
Highly Cited
1988
The mechanism of hepatocarcinogenesis caused by peroxisome proliferators (PP) is poorly understood, making it difficult to… (More)
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