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WRN gene

Known as: RECQL2, DNA HELICASE, RECQ-LIKE, TYPE 3, RECQ3 
This gene is involved in DNA repair and the unwinding of DNA.
National Institutes of Health

Related topics

Related topics

13 relations
BLM geneBLM wt AlleleBase Excision RepairDNA Repair

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Abstract PR08: Altered nucleolar trafficking of the Blm helicase in the mouse reduces size, increases DNA damage and tumor susceptibility, and facilitates premature aging
Bloom9s syndrome (BS) is a recessive human chromosome breakage disorder caused by mutations in the recQ-like helicase BLM… 
2017
2017
WRN, the Werner Syndrome Gene, Exhibits Frameshift Mutations in Gastric and Colorectal Cancers
To the Editor Werner syndrome, an autosomal recessive disorder causing premature aging, is caused by truncating mutations in… 
2012
2012
Mechanisms of replicative senescence in Werner's syndrome cells
One of the causes of ageing is thought to be the accumulation of senescent cells. Since normal ageing is very complex, diseases… 
2011
2011
Primary liver tumor associated with Werner syndrome (adult progeria)
A 57‐year‐old woman was admitted to our hospital with characteristic aging of the face and thin body. Before admission, she had… 
Review
2004
Review
2004
Functional Link Between Myc and the Werner Gene in Tumorigenesis
We have recently reported a connection between the expression of the Werner syndrome gene (WRN), whose loss of function has been… 
Review
2000
Review
2000
Comparative aspects of the Werner syndrome gene.
Werner syndrome (WS) ("Progeria of the adult"; entry *27770 (1)) was originally defined by Dr. Otto Werner in 1904 on the basis… 
1998
1998
Comparison of methods for identifying transcription units and transcription map of the Werner syndrome gene region.
To isolate a human disease gene by positional cloning, a critical step is the identification of candidate genes from a targeted… 
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