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WP 631

Known as: WP-631, WP631 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2018
02419972018

Related topics

Related topics

1 relation

Broader (1)

Daunorubicin

Related mentions per year

Related mentions per year

1954-2018
1960198020002020
WP 631
Daunorubicin

Papers overview

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2015
2015
Metformin, but not sitagliptin, enhances WP 631-induced apoptotic HepG2 cell death.
Metformin and sitagliptin are hypoglycemic drugs with potential use in cancer treatment. Evidence indicates that metformin may… (More)
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2014
2014
Pro-apoptotic activity of new analog of anthracyclines--WP 631 in advanced ovarian cancer cell line.
In this work we investigated the mode of cell death induced by WP 631, a novel anthracycline antibiotic, in the ovarian cancer… (More)
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2011
2011
The role of reactive oxygen species in WP 631-induced death of human ovarian cancer cells: a comparison with the effect of doxorubicin.
In the present study, we investigated the anticancer activity of WP 631, a new anthracycline analog, in weakly doxorubicin… (More)
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2007
2007
Sp1-mediated transcription is involved in the induction of leptin by insulin-stimulated glucose metabolism.
We have previously demonstrated that insulin-stimulated glucose metabolism, and not insulin per se, mediates the effects of… (More)
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2007
2007
Epithelial-mesenchymal interactions in keloid pathogenesis modulate vascular endothelial growth factor expression and secretion.
Vascular endothelial growth factor (VEGF) plays an important role in angiogenesis during the wound healing process. As epithelial… (More)
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Highly Cited
2006
Highly Cited
2006
Mitotic catastrophe results in cell death by caspase-dependent and caspase-independent mechanisms.
Exposure of MDA-MB-231 and MCF-7/VP human breast carcinoma cells to the anthracyclines doxorubicin and WP631 induced polyploidy… (More)
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2006
2006
Upregulation of secretory connective tissue growth factor (CTGF) in keratinocyte-fibroblast coculture contributes to keloid pathogenesis.
Connective tissue growth factor (CTGF) plays a critical role in keloid pathogenesis by promoting collagen synthesis and… (More)
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2004
2004
Evidence that activation of nuclear factor-kappaB is essential for the cytotoxic effects of doxorubicin and its analogues.
Several reports within the last 5 years have suggested that nuclear factor (NF)-kappaB activation suppresses apoptosis through… (More)
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2004
2004
Bis-anthracycline antibiotics inhibit human immunodeficiency virus type 1 transcription.
The increasing numbers of human immunodeficiency virus type 1 (HIV-1) strains that exhibit resistance to antiretroviral agents… (More)
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2001
2001
Identification of a critical Sp1 site within the endoglin promoter and its involvement in the transforming growth factor-beta stimulation.
Endoglin, a component of the transforming growth factor-beta (TGF-beta) receptor complex expressed on endothelial cells, is… (More)
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