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WP 631

Known as: WP-631, WP631 
 
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Vascular endothelial growth factor (VEGF) plays an important role in angiogenesis during the wound healing process. As epithelial… Expand
Highly Cited
2006
Highly Cited
2006
Exposure of MDA-MB-231 and MCF-7/VP human breast carcinoma cells to theanthracyclines doxorubicin and WP631 induced polyploidy… Expand
Highly Cited
2005
Highly Cited
2005
Transforming growth factor (TGF‐β1) is a potent inducer of chondrogenesis and stimulant of cartilage extracellular matrix (ECM… Expand
Highly Cited
2005
Highly Cited
2005
A new bisintercalating anthracycline (WP762) has been designed, in which monomeric units of daunorubicin have been linked through… Expand
2002
2002
WP631, a new DNA-binding drug that bisintercalates into DNA with high affinity, seems to be highly cytotoxic against Jurkat T… Expand
Highly Cited
2001
Highly Cited
2001
Endoglin, a component of the transforming growth factor-β (TGF-β) receptor complex expressed on endothelial cells, is involved in… Expand
Highly Cited
1999
Highly Cited
1999
An in vitro transcription assay was used to compare the capacity of the bisintercalating anthracycline WP631 (which displays a… Expand
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Highly Cited
1998
Highly Cited
1998
Differential scanning calorimetry and absorption spectroscopy were used to characterize the interaction of the new… Expand
Highly Cited
1997
Highly Cited
1997
A new bisintercalating anthracycline antibiotic, WP631, has been designed and synthesized. The rational design of the new… Expand
1997
1997
The application of detailed structural data bases has now culminated in the successful design of a new generation of… Expand