WNK4 gene

Known as: WNK4, PROTEIN KINASE, LYSINE-DEFICIENT 4, PRKWNK4 
 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Pseudohypoaldosteronism type II (PHAII) is a rare Mendelian syndrome featuring hypertension and hyperkalemia resulting from… (More)
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Highly Cited
2009
Highly Cited
2009
Mutations in the kinase WNK4 cause pseudohypoaldosteronism type II (PHAII), a syndrome featuring hypertension and high serum K… (More)
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Highly Cited
2007
Highly Cited
2007
The steroid hormone aldosterone is secreted both in the setting of intravascular volume depletion and hyperkalemia, raising the… (More)
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Highly Cited
2006
Highly Cited
2006
In the present study, we have demonstrated functional interaction between Ste20-related proline-alanine-rich kinase (SPAK), WNK4… (More)
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Highly Cited
2006
Highly Cited
2006
Pseudohypoaldosteronism type II (PHA II) is caused by mutations of two members of WNK ((with no lysine (k)) kinase family. WNK4… (More)
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Highly Cited
2005
Highly Cited
2005
With-no-lysine (WNK) kinases are highly expressed along the mammalian distal nephron. Mutations in either WNK1 or WNK4 cause… (More)
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Highly Cited
2004
Highly Cited
2004
Mutations in the WNK4 gene cause pseudohypoaldosteronism type II (PHAII), an autosomal-dominant disorder of hyperkalemia and… (More)
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Highly Cited
2004
Highly Cited
2004
Paracellular ion flux across epithelia occurs through selective and regulated pores in tight junctions; this process is poorly… (More)
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Highly Cited
2003
Highly Cited
2003
A key question in systems biology is how diverse physiologic processes are integrated to produce global homeostasis. Genetic… (More)
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Highly Cited
2003
Highly Cited
2003
Mutations in the serine-threonine kinases WNK1 and WNK4 [with no lysine (K) at a key catalytic residue] cause… (More)
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