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WNK4 gene

Known as: WNK4, PROTEIN KINASE, LYSINE-DEFICIENT 4, PRKWNK4 
 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Pseudohypoaldosteronism type II (PHAII) is a rare Mendelian syndrome featuring hypertension and hyperkalemia resulting from… Expand
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Highly Cited
2009
Highly Cited
2009
We recently generated Wnk4(D561A/+) knockin mice and found that a major pathogenesis of pseudohypoaldosteronism type II was the… Expand
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Highly Cited
2009
Highly Cited
2009
Mutations in the kinase WNK4 cause pseudohypoaldosteronism type II (PHAII), a syndrome featuring hypertension and high serum K… Expand
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Highly Cited
2006
Highly Cited
2006
In the present study, we have demonstrated functional interaction between Ste20-related proline-alanine-rich kinase (SPAK), WNK4… Expand
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Highly Cited
2005
Highly Cited
2005
Mutations in the human genes encoding WNK1 [with no K (lysine) protein kinase-1] and the related protein kinase WNK4 are the… Expand
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Highly Cited
2004
Highly Cited
2004
Mutations in the WNK4 gene cause pseudohypoaldosteronism type II (PHAII), an autosomal-dominant disorder of hyperkalemia and… Expand
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Highly Cited
2004
Highly Cited
2004
Paracellular ion flux across epithelia occurs through selective and regulated pores in tight junctions; this process is poorly… Expand
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Highly Cited
2003
Highly Cited
2003
A key question in systems biology is how diverse physiologic processes are integrated to produce global homeostasis. Genetic… Expand
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Highly Cited
2003
Highly Cited
2003
Mutations in the serine-threonine kinases WNK1 and WNK4 [with no lysine (K) at a key catalytic residue] cause… Expand
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Highly Cited
2003
Highly Cited
2003
Pseudohypoaldosteronism type II (PHAII) is an autosomal dominant disorder of hyperkalemia and hypertension. Mutations in two… Expand
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