WNK1 gene

Known as: PPP1R167, KIAA0344, protein phosphatase 1, regulatory subunit 167 
This gene plays a role in regulation of electrolyte homeostasis.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2018
010203019952018

Papers overview

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Highly Cited
2006
Highly Cited
2006
The SPAK (STE20/SPS1-related proline/alanine-rich kinase) and OSR1 (oxidative stress-responsive kinase-1) kinases interact and… (More)
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Highly Cited
2006
Highly Cited
2006
WNK kinases are serine-threonine kinases with an atypical placement of the catalytic lysine. Intronic deletions with increased… (More)
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Highly Cited
2005
Highly Cited
2005
Mutations in the human genes encoding WNK1 [with no K (lysine) protein kinase-1] and the related protein kinase WNK4 are the… (More)
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Highly Cited
2005
Highly Cited
2005
The WNK1 and WNK4 genes have been found to be mutated in some patients with hyperkalemia and hypertension caused by… (More)
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Highly Cited
2005
Highly Cited
2005
WNK (with no lysine [K]) kinases are serine-threonine protein kinases with an atypical placement of the catalytic lysine… (More)
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Highly Cited
2005
Highly Cited
2005
With-no-lysine (WNK) kinases are highly expressed along the mammalian distal nephron. Mutations in either WNK1 or WNK4 cause… (More)
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Highly Cited
2003
Highly Cited
2003
The availability of both the mouse and human genome sequences allows for the systematic discovery of human gene function through… (More)
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Highly Cited
2003
Highly Cited
2003
WNK1 is a serine-threonine kinase, the expression of which is affected in pseudohypoaldosteronism type II, a Mendelian form of… (More)
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Highly Cited
2003
Highly Cited
2003
WNK1 is a member of a novel serine/threonine kinase family, With-No-K, (lysine). Intronic deletions in the encoding gene cause… (More)
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Highly Cited
2000
Highly Cited
2000
We have cloned and characterized a novel mammalian serine/threonine protein kinase WNK1 (with no lysine (K)) from a rat brain… (More)
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