WHSC1 gene

Known as: WOLF-HIRSCHHORN SYNDROME CANDIDATE 1, MMSET, MULTIPLE MYELOMA SET DOMAIN 
This gene is involved in development and the suppression of nucleotide transcription.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Mantle cell lymphoma (MCL) is an aggressive tumor, but a subset of patients may follow an indolent clinical course. To understand… (More)
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Highly Cited
2011
Highly Cited
2011
The multiple myeloma SET domain (MMSET) protein is overexpressed in multiple myeloma (MM) patients with the translocation t(4;14… (More)
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Highly Cited
2011
Highly Cited
2011
p53-binding protein 1 (53BP1) is known to be an important mediator of the DNA damage response, with dimethylation of histone H4… (More)
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Highly Cited
2009
Highly Cited
2009
Diverse histone modifications are catalysed and recognized by various specific proteins, establishing unique modification… (More)
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Highly Cited
2008
Highly Cited
2008
Multiple myeloma (MM) is an incurable hematologic malignancy characterized by recurrent chromosomal translocations. Patients with… (More)
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Highly Cited
2006
Highly Cited
2006
To better define the molecular basis of multiple myeloma (MM), we performed unsupervised hierarchic clustering of mRNA expression… (More)
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2006
2006
BACKGROUND AND OBJECTIVES Multiple myeloma (MM) is a malignancy characterized by clonal expansion of plasma cells. In 50% of the… (More)
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Highly Cited
2004
Highly Cited
2004
The t(4;14)(p16.3;q32), associated with 10–20% of cases of multiple myeloma (MM), deregulates the expression of MMSET and FGFR3… (More)
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Highly Cited
2003
Highly Cited
2003
Previous studies have revealed that that approximately 10% to 15% of multiple myelomas (MMs) are characterized by a reciprocal t… (More)
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Highly Cited
1998
Highly Cited
1998
Previously we reported that a karyotypically silent t(4;14)(p16. 3;q32.3) translocation is present in about 25% of multiple… (More)
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