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WHSC1 gene

Known as: WOLF-HIRSCHHORN SYNDROME CANDIDATE 1, MMSET, MULTIPLE MYELOMA SET DOMAIN 
This gene is involved in development and the suppression of nucleotide transcription.
National Institutes of Health

Related topics

Related topics

4 relations
MethylationProtein methylationWHSC1 protein, humanWolf-Hirschhorn Syndrome

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
DICER- and MMSET-catalyzed H4K20me2 recruits the nucleotide excision repair factor XPA to DNA damage sites
Ultraviolet (UV) irradiation triggers the recruitment of DNA repair factors to the lesion sites and the deposition of histone… 
2017
2017
Wolf–Hirschhorn Syndrome Candidate 1 (whsc1) Functions as a Tumor Suppressor by Governing Cell Differentiation
Highly Cited
2011
Highly Cited
2011
MMSET is highly expressed and associated with aggressiveness in neuroblastoma.
MMSET (WHSC1/NSD2) is a SET domain-containing histone lysine methyltransferase the expression of which is deregulated in a… 
2010
2010
Interstitial microdeletion of 4p16.3: Contribution of WHSC1 haploinsufficiency to the pathogenesis of developmental delay in Wolf–Hirschhorn syndrome
Interstitial Microdeletion of 4p16.3: Contribution of WHSC1 Haploinsufficiency to the Pathogenesis of Developmental Delay in Wolf… 
2007
2007
Detection and follow‐up of fibroblast growth factor receptor 3 expression on bone marrow and circulating plasma cells by flow cytometry in patients with t(4;14) multiple myeloma
The t(4;14)(p16;q32) translocation, found in 15% of multiple myeloma (MM) cases, indicates a poor prognosis. Plasma cells (PC… 
2005
2005
Evaluation of NSD2 and NSD3 in overgrowth syndromes
Sotos syndrome is an overgrowth condition predominantly caused by truncating mutations, missense mutations restricted to… 
Highly Cited
2004
Highly Cited
2004
A Global Expression-based Analysis of the Consequences of the t(4;14) Translocation in Myeloma
Purpose: Our purpose in this report was to define genes and pathways dysregulated as a consequence of the t(4;14) in myeloma, and… 
2004
2004
Propofol offers no advantage over isoflurane anesthesia for cerebral protection during cardiopulmonary bypass: a preliminary study of S-100ß protein levels
PurposeDespite advances in anesthesia, cardiopulmonary bypass (CPB) and surgical techniques, cerebral injury remains a major… 
Highly Cited
2003
Highly Cited
2003
Mutation, SNP, and isoform analysis of fibroblast growth factor receptor 3 (FGFR3) in 150 newly diagnosed multiple myeloma patients.
The t(4;14) translocation in multiple myeloma (MM) is identified in 15% of patient samples and dysregulates both FGFR3 and… 
Review
2002
Review
2002
The enigma of ectopic expression of FGFR3 in multiple myeloma: a critical initiating event or just a target for mutational activation during tumor progression.
The t(4;14)(p16.3;q32) translocation that occurs uniquely in a subset of multiple myeloma tumors results in ectopic expression of… 
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