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WHI-05

Known as: WHI 05 
National Institutes of Health

Papers overview

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2011
2011
Contraceptive activity of a spermicidal aryl phosphate derivative of bromo-methoxy zidovudine (compound WHI-05) in rabbits.
WHI-05 (5-bromo-6-methoxy-5,6-dihydro-3'-azidothymidine-5'-(p-methoxyphenyl) methoxyalaninyl phosphate, CAS 213982-93-5) is a… 
2002
2002
Pre-clinical safety evaluation of novel nucleoside analogue-based dual-function microbicides (WHI-05 and WHI-07).
Compounds WHI-05 [5-bromo-6-methoxy-5,6-dihydro-3'-azidothymidine-5'-(p-methoxyphenyl)-methoxyalaninyl phosphate] and WHI-07 [5… 
2002
2002
In vivo contraceptive activity of novel dual-function microbicides: aryl phosphate derivatives of bromo-methoxy zidovudine (compounds WHI-05 and WHI-07)
2001
2001
Thymidine Kinase-Independent Intracellular Delivery of Bioactive Nucleotides by Aryl Phosphate Derivatives of Bromo-Methoxy Zidovudine (Compounds WHI-05 and WHI-07) in Normal Human Female Genital…
Abstract The compounds WHI-05 (5-bromo-6-methoxy-5,6-dihydro-3′-azidothymidine-5′-[p-methoxyphenyl] methoxyalaninyl phosphate… 
2000
2000
Evaluation of subchronic (13‐week) and reproductive toxicity potential of intravaginal gel–microemulsion formulation of a dual‐function phenyl phosphate derivative of bromo‐methoxy zidovudine…
Heterosexual transmission of human immunodeficiency virus (HIV) accounts for 90% of all new infections worldwide and… 
2000
2000
Evaluation of subchronic (13 weeks) and reproductive toxicity potential of intravaginal gel-microemulsion formulation of a dual-function phenyl phosphate derivative of bromo-methoxy zidovudine…
Review
1999
Review
1999
Prophylactic contraceptives for HIV/AIDS.
The current pandemic of sexually transmitted human immunodeficiency virus (HIV) infection--the causative agent of acquired… 
1999
1999
WHI-05, a novel bromo-methoxy substituted phenyl phosphate derivative of zidovudine, is a dual-action spermicide with potent anti-HIV activity.
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