Viral Interleukin-6 Homolog

Known as: Putative Interleukin 6, ORF K2, vIL-6 
Viral interleukin-6 homolog (204 aa, ~23 kDa) is encoded by the human herpesvirus 8 K2 gene. This protein is involved in the negative regulation of… (More)
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
BACKGROUND Kaposi sarcoma-associated herpesvirus (KSHV) is the causal agent for Kaposi sarcoma (KS) and multicentric Castleman… (More)
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Highly Cited
1999
Highly Cited
1999
Primary effusion lymphoma (PEL) is a distinct type of lymphoma associated with Kaposi's sarcoma-associated herpesvirus (KSHV… (More)
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Highly Cited
1999
Highly Cited
1999
Human herpesvirus 8 (HHV-8) infection has been implicated in the etiology of Kaposi's sarcoma (KS), primary effusion lymphoma… (More)
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Highly Cited
1999
Highly Cited
1999
Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8 [HHV-8]) is a herpesvirus linked to the… (More)
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Highly Cited
1999
Highly Cited
1999
Kaposi's sarcoma-associated herpesvirus (KSHV or HHV8) encodes a structural and functional homologue of human IL-6 called viral… (More)
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Highly Cited
1998
Highly Cited
1998
Seroepidemiology and polymerase chain reaction studies have strongly suggested that human herpesvirus type 8 (HHV-8) is… (More)
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Highly Cited
1997
Highly Cited
1997
Kaposi's sarcoma is a multifocal lesion that is reported to be greatly influenced by cytokines such as interleukin-6 (IL-6) and… (More)
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Highly Cited
1997
Highly Cited
1997
The present studies analyzed the biologic activity of a gene product (vIL-6) encoded by the recently discovered Kaposi's sarcoma… (More)
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Highly Cited
1997
Highly Cited
1997
Castleman's disease is a rare B cell lymphoproliferative disorder related to excess interleukin-6 (IL-6)-like activity. Kaposi's… (More)
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Highly Cited
1996
Highly Cited
1996
Four virus proteins similar to two human macrophage inflammatory protein (MIP) chemokines, interleukin-6 (IL-6), and interferon… (More)
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