Vesicular Monoamine Transport Proteins

Known as: Vesicular Transporter, Monoamine, Vesicular Monoamine Transporter Proteins, Monoamine Transporters, Vesicular 
A family of vesicular amine transporter proteins that catalyze the transport and storage of CATECHOLAMINES and indolamines into SECRETORY VESICLES.
National Institutes of Health

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In BloodProcess of secretionagonistsantagonists & inhibitors
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Slc18a1 protein, ratSlc18a2 protein, ratVesicular Monoamine Transporter 2chromaffin granule amine transporter

Papers overview

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Highly Cited
1999
Highly Cited
1999
The cat-1 gene of Caenorhabditis elegans encodes a vesicular monoamine transporter required for specific monoamine-dependent behaviors.
We have identified the Caenorhabditis elegans homolog of the mammalian vesicular monoamine transporters (VMATs); it is 47… (More)
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Highly Cited
1999
Highly Cited
1999
Increased methamphetamine neurotoxicity in heterozygous vesicular monoamine transporter 2 knock-out mice.
Methamphetamine (METH) is a powerful psychostimulant that is increasingly abused worldwide. Although it is commonly accepted that… (More)
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Highly Cited
1997
Highly Cited
1997
Identification and characterization of the vesicular GABA transporter
Synaptic transmission involves the regulated exocytosis of vesicles filled with neurotransmitter. Classical transmitters are… (More)
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Highly Cited
1997
Highly Cited
1997
Knockout of the Vesicular Monoamine Transporter 2 Gene Results in Neonatal Death and Supersensitivity to Cocaine and Amphetamine
Vesicular monoamine transporters are known to transport monoamines from the cytoplasm into secretory vesicles. We have used… (More)
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Review
1997
Review
1997
The role of vesicular transport proteins in synaptic transmission and neural degeneration.
Classical neurotransmitters are synthesized in the cytoplasm, so they require transport into secretory vesicles for regulated… (More)
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Highly Cited
1997
Highly Cited
1997
Vesicular Transport Regulates Monoamine Storage and Release but Is Not Essential for Amphetamine Action
To assess the role of exocytotic release in signaling by monoamines, we have disrupted the neuronal vesicular monoamine… (More)
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Highly Cited
1996
Highly Cited
1996
Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporter.
A second isoform of the human vesicular monoamine transporter (hVMAT) has been cloned from a pheochromocytoma cDNA library. The… (More)
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Highly Cited
1995
Highly Cited
1995
Differential expression of two vesicular monoamine transporters.
Specific transport proteins package classical neurotransmitters into vesicles so that their release can be regulated by neural… (More)
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Highly Cited
1994
Highly Cited
1994
Localization of vesicular monoamine transporter isoforms (VMAT1 and VMAT2) to endocrine cells and neurons in rat
Polyclonal antipeptide antibodies have been raised against each of the two isoforms of the rat vesicular monoamine transporter… (More)
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Highly Cited
1992
Highly Cited
1992
Expression cloning of a reserpine-sensitive vesicular monoamine transporter.
A cDNA for a rat vesicular monoamine transporter, designated MAT, was isolated by expression cloning in a mammalian cell line (CV… (More)
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