Author pages are created from data sourced from our academic publisher partnerships and public sources.
Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome)
To improve the specificity and sensitivity of the clinical diagnosis of progressive supranuclear palsy (PSP, Steele-Richardson-Olszewski syndrome), the National Institute of Neurological Disorders… Expand
The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease.
- P. Damier, E. Hirsch, Y. Agid, A. Graybiel
- Medicine, Biology
- Brain : a journal of neurology
- 1 August 1999
To achieve accuracy in studying the patterns of loss of midbrain dopamine-containing neurons in Parkinson's disease, we used compartmental patterns of calbindin D(28K) immunostaining to subdivide the… Expand
Partially overlapping neural networks for real and imagined hand movements.
Neuroimagery findings have shown similar cerebral networks associated with imagination and execution of a movement. On the other hand, neuropsychological studies of parietal-lesioned patients suggest… Expand
Clinical and genetic abnormalities in patients with Friedreich's ataxia.
BACKGROUND Friedreich's ataxia, the most common inherited ataxia, is associated with a mutation that consists of an unstable expansion of GAA repeats in the first intron of the frataxin gene on… Expand
The Mental Representation of Hand Movements After Parietal Cortex Damage
- A. Sirigu, J. Duhamel, L. Cohen, B. Pillon, B. Dubois, Y. Agid
- Psychology, Medicine
- 13 September 1996
Recent neuroimagery findings showed that the patterns of cerebral activation during the mental rehearsal of a motor act are similar to those produced by its actual execution. This concurs with the… Expand
Bilateral deep brain stimulation in Parkinson's disease: a multicentre study with 4 years follow-up.
- M. Rodriguez-Oroz, J. Obeso, +26 authors N. Van Blercom
- Brain : a journal of neurology
- 1 October 2005
Deep brain stimulation (DBS) is associated with significant improvement of motor complications in patients with severe Parkinson's disease after some 6-12 months of treatment. Long-term results in a… Expand
Parkinson’s disease and sleepiness: An integral part of PD
ObjectiveTo investigate the potential causes of excessive daytime sleepiness in patients with PD—poor sleep quality, abnormal sleep–wakefulness control, and treatment with dopaminergic agents.… Expand
Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease
In idiopathic Parkinson's disease massive cell death occurs in the dopamine-containing substantia nigra1,24. A link between the vulnerability of nigral neurons and the prominent pigmentation of the… Expand
Basal Lipid Peroxidation in Substantia Nigra Is Increased in Parkinson's Disease
- D. Dexter, C. Carter, +5 authors C. Marsden
- Biology, Medicine
- Journal of neurochemistry
- 1 February 1989
Abstract: Polyunsaturated fatty acid (PUFA) levels (an index of the amount of substrate available for lipid peroxidation) were measured in several brain regions from patients who died with… Expand
Increased Nigral Iron Content and Alterations in Other Metal Ions Occurring in Brain in Parkinson's Disease
Abstract: Levels of iron, copper, zinc, manganese, and lead were measured by inductively coupled plasma spectroscopy in parkinsonian and age‐matched control brain tissue. There was 31‐35% increase in… Expand