VMAT2 gene expression and function as it applies to imaging β-cell mass

  title={VMAT2 gene expression and function as it applies to imaging β-cell mass},
  author={P. Harris and C. Ferrara and P. Barba and Teresa Polito and M. Freeby and A. Maffei},
  journal={Journal of Molecular Medicine},
  • P. Harris, C. Ferrara, +3 authors A. Maffei
  • Published 2007
  • Biology
  • Journal of Molecular Medicine
  • Diabetes mellitus is a metabolic disorder characterized by hyperglycemia. The two main forms of the disease are distinguished by different pathogenesis, natural histories, and population distributions and indicated as either type 1 (T1DM) or type 2 diabetes mellitus (T2DM). It is well established that T1DM is an autoimmune disease whereby β-cells of pancreatic islets are destroyed leading to loss of endogenous insulin production. Albeit less dramatic, β-cell mass (BCM) also drops in T2DM… CONTINUE READING
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