VMAT2 gene expression and function as it applies to imaging β-cell mass

@article{Harris2007VMAT2GE,
  title={VMAT2 gene expression and function as it applies to imaging $\beta$-cell mass},
  author={Paul E Harris and Caterina Ferrara and Pasquale Barba and Teresa Polito and Matthew Freeby and Antonella Maffei},
  journal={Journal of Molecular Medicine},
  year={2007},
  volume={86},
  pages={5-16}
}
Diabetes mellitus is a metabolic disorder characterized by hyperglycemia. The two main forms of the disease are distinguished by different pathogenesis, natural histories, and population distributions and indicated as either type 1 (T1DM) or type 2 diabetes mellitus (T2DM). It is well established that T1DM is an autoimmune disease whereby β-cells of pancreatic islets are destroyed leading to loss of endogenous insulin production. Albeit less dramatic, β-cell mass (BCM) also drops in T2DM… Expand

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