Vascular Smooth Muscle Contraction Pathway

Known as: Vascular smooth muscle contraction 
A process, occurring in the vascular tissue, whereby actin/myosin complex activity generates force through ATP hydrolysis resulting in a change in… (More)
National Institutes of Health

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ACTA2 wt AlleleADCY9 protein, humanADORA2A wt AlleleADRA1A protein, human
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Papers overview

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Highly Cited
2009
Highly Cited
2009
ROCK isoform regulation of myosin phosphatase and contractility in vascular smooth muscle cells.
Abnormal vascular smooth muscle cell (VSMC) contraction plays an important role in vascular diseases. The RhoA/ROCK signaling… (More)
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Highly Cited
2005
Highly Cited
2005
Thromboxane A2-induced contraction of rat caudal arterial smooth muscle involves activation of Ca2+ entry and Ca2+ sensitization: Rho-associated kinase-mediated phosphorylation of MYPT1 at Thr-855…
The signal transduction pathway whereby the TxA2 (thromboxane A2) mimetic U-46619 activates vascular smooth muscle contraction… (More)
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Review
2004
Review
2004
Gender, sex hormones, and vascular tone.
The greater incidence of hypertension and coronary artery disease in men and postmenopausal women compared with premenopausal… (More)
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Highly Cited
2003
Highly Cited
2003
Ca2+-dependent activation of Rho and Rho kinase in membrane depolarization-induced and receptor stimulation-induced vascular smooth muscle contraction.
Ca2+ sensitization of vascular smooth muscle (VSM) contraction involves Rho-dependent and Rho-kinase-dependent suppression of… (More)
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2003
2003
Role of Crk-associated substrate in the regulation of vascular smooth muscle contraction.
A pool of actin monomers is induced to polymerize into actin filaments during contractile stimulation of smooth muscle. The… (More)
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Review
2002
Review
2002
Vascular mechanisms of increased arterial pressure in preeclampsia: lessons from animal models.
Normal pregnancy is associated with reductions in total vascular resistance and arterial pressure possibly due to enhanced… (More)
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Highly Cited
1987
Highly Cited
1987
Vascular muscle cell depolarization and activation in renal arteries on elevation of transmural pressure.
The goal of this study was to define some of the cellular and ionic mechanisms of smooth muscle cell activation in dog renal… (More)
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Review
1986
Review
1986
Modulation of vascular smooth muscle contraction by the endothelium.
 
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1984
1984
TPA-induced contraction of isolated rabbit vascular smooth muscle.
Myosin light chain phosphorylation may not regulate the sustained phase of vascular smooth muscle contraction. Another… (More)
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1968
1968
Oxygen and vascular smooth muscle contraction.
DETAR, REED, AND DAVID F. BOHR. Oxygen and vascular smooth muscle contraction. Am. J. Physiol. 214(Z): 241-244. 1968.-Oxygen… (More)
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