VDJ Recombinases

Known as: VDJ Recombinases [Chemical/Ingredient], V(D)J Recombinase, V D J Recombinase 
Recombinases involved in the rearrangement of immunity-related GENES such as IMMUNOGLOBULIN GENES and T-CELL RECEPTOR GENES.
National Institutes of Health

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Highly Cited
2001
Highly Cited
2001
Adenocarcinoma of the lung is the most common form of lung cancer, but the cell of origin and the stages of progression of this… (More)
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Highly Cited
2001
Highly Cited
2001
The advent of conditional and tissue-specific recombination systems in gene-targeted or transgenic mice has permitted an… (More)
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Highly Cited
1997
Highly Cited
1997
Ligand-dependent chimeric Cre recombinases are powerful tools to induce specific DNA rearrangements in cultured cells and in mice… (More)
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Highly Cited
1997
Highly Cited
1997
The Cre/loxP site-specific recombination system derived from bacteriophage P1 provides a convenient tool for directed… (More)
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Highly Cited
1997
Highly Cited
1997
The production of subtle or conditional mutations in mice through the combined use of site-specific and homologous recombination… (More)
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Highly Cited
1997
Highly Cited
1997
Mouse models of human disease can be generated by homologous recombination for germline loss-of-function mutations. However… (More)
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Highly Cited
1995
Highly Cited
1995
We have developed a strategy to generate mutant genes in mammalian cells in a conditional manner by employing a fusion protein… (More)
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Highly Cited
1992
Highly Cited
1992
We have developed a method of specifically modifying the mammalian genome in vivo. This procedure comprises heritable tissue… (More)
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Highly Cited
1988
Highly Cited
1988
The Cre protein encoded by the coliphage P1 is a 38-kDa protein that efficiently promotes both intra- and intermolecular synapsis… (More)
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Highly Cited
1988
Highly Cited
1988
Abelson murine leukemia virus-transformed precursor B lymphocytes from scid (severe combined immunodeficient) mice, like A-MuLV… (More)
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