VDAC1 gene

Known as: VOLTAGE-DEPENDENT ANION CHANNEL 1, voltage dependent anion channel 1, Voltage-Dependent Anion Channel 1 Gene 
This gene is involved in the regulation of small molecule transport through the outer mitochondrial membrane.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Voltage-dependent anion channels (VDACs) are expressed in three isoforms, with common channeling properties and different roles… (More)
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Highly Cited
2010
Highly Cited
2010
Parkinson's disease is the most common neurodegenerative movement disorder. Mutations in PINK1 and PARKIN are the most frequent… (More)
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Highly Cited
2010
Highly Cited
2010
Mitochondria sustain damage with aging, and the resulting mitochondrial dysfunction has been implicated in a number of diseases… (More)
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Highly Cited
2010
Highly Cited
2010
Mutations in superoxide dismutase (SOD1) cause amyotrophic lateral sclerosis (ALS), a neurodegenerative disease characterized by… (More)
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Highly Cited
2009
Highly Cited
2009
The release of mitochondrial-intermembrane-space pro-apoptotic proteins, such as cytochrome c, is a key step in initiating… (More)
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Highly Cited
2008
Highly Cited
2008
The voltage-dependent anion channel (VDAC) constitutes the major pathway for the entry and exit of metabolites across the outer… (More)
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Highly Cited
2006
Highly Cited
2006
Opening of the permeability transition pore (PTP), a high-conductance mitochondrial channel, causes mitochondrial dysfunction… (More)
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Highly Cited
2006
Highly Cited
2006
The voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane mediates metabolic flow, Ca(2+), and cell death… (More)
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Highly Cited
2005
Highly Cited
2005
The influenza virus PB1-F2 is an 87-amino acid mitochondrial protein that previously has been shown to induce cell death… (More)
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Highly Cited
2003
Highly Cited
2003
The multidomain proapoptotic molecules BAK or BAX are required to initiate the mitochondrial pathway of apoptosis. How cells… (More)
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