VCP protein, human

Known as: 15S Mg(2+)-ATPase P97 Subunit, VCP, Epididymis Secretory Protein Li 70 
Transitional endoplasmic reticulum ATPase (806 aa, ~89 kDa) is encoded by the human VCP gene. This protein is involved in maintaining the Golgi… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Stress granules and P bodies are conserved cytoplasmic aggregates of nontranslating messenger ribonucleoprotein complexes (mRNPs… (More)
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Highly Cited
2013
Highly Cited
2013
In Alzheimer's disease (AD), the mechanisms of neuronal loss remain largely unknown. Although tau pathology is closely correlated… (More)
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Review
2012
Review
2012
The ATP-driven chaperone valosin-containing protein (VCP)/p97 governs critical steps in ubiquitin-dependent protein quality… (More)
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Highly Cited
2011
Highly Cited
2011
Unrepaired DNA double-strand breaks (DSBs) cause genetic instability that leads to malignant transformation or cell death. Cells… (More)
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Highly Cited
2010
Highly Cited
2010
VCP (VCP/p97) is a ubiquitously expressed member of the AAA(+)-ATPase family of chaperone-like proteins that regulates numerous… (More)
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Highly Cited
2007
Highly Cited
2007
Mutations in p97/VCP cause the autosomal-dominant, inherited syndrome inclusion body myopathy (IBM) associated with Paget's… (More)
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Highly Cited
2006
Highly Cited
2006
Mutations in the AAA+ protein (ATPase associated with a variety of cellular activities) p97/VCP (valosin-containing protein… (More)
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Highly Cited
2006
Highly Cited
2006
Frontotemporal dementia (FTD) with inclusion body myopathy and Paget disease of bone (IBMPFD) is a rare, autosomal-dominant… (More)
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Highly Cited
2004
Highly Cited
2004
We have used RNA interference (RNAi) to examine the functional relationship between valosin-containing protein (VCP/p97/Cdc48p… (More)
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Highly Cited
2003
Highly Cited
2003
Before fertilization can occur, mammalian sperm must undergo capacitation, a process that requires a cyclic AMP-dependent… (More)
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