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Oocyte apoptosis during the transition from ovary-like tissue to testes during sex differentiation of juvenile zebrafish.
Large numbers of apoptotic early diplotene oocytes were observed during the transition from ovary-like undifferentiated gonadal tissue to testes during sex differentiation in presumptive males of theExpand
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An aromatase inhibitor or high water temperature induce oocyte apoptosis and depletion of P450 aromatase activity in the gonads of genetic female zebrafish during sex-reversal.
Dietary administration of a cytochrome P450 aromatase (P450arom) inhibitor (fadrozole) in genetic female juveniles of zebrafish (Danio rerio) was performed at 15-40 days post-hatching. The percentageExpand
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Mutations in KLHL40 are a frequent cause of severe autosomal-recessive nemaline myopathy.
Nemaline myopathy (NEM) is a common congenital myopathy. At the very severe end of the NEM clinical spectrum are genetically unresolved cases of autosomal-recessive fetal akinesia sequence. WeExpand
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The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity.
Statins inhibit HMG-CoA reductase, a key enzyme in cholesterol synthesis, and are widely used to treat hypercholesterolemia. These drugs can lead to a number of side effects in muscle, includingExpand
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Quantitative mRNA expression profiling of heat-shock protein families in rainbow trout cells.
We isolated multiple HSPs from rainbow trout Oncorhynchus mykiss RTG-2 cells and quantitatively compared their mRNA levels between unstressed and heat-shocked cells using real-time RT-PCR analysis.Expand
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High activities of cathepsins B, D, H, and L in the white muscle of chum salmon in spawning migration.
1. Activities of cathepsins, lysosomal hydrolytic enzymes and cysteine protease inhibitor in both the white and red muscles of chum salmon (Oncorhynchus keta) caught during spawning and feedingExpand
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Purification and characterization of maturation-promoting factor in fish.
Maturation-promoting factor (MPF) activity has been demonstrated for the first time in fish oocytes. We purified MPF from a 100,000g supernatant of crushed, naturally spawned carp oocytes using fourExpand
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Characterization of multiple members of the HSP70 family in platyfish culture cells: molecular evolution of stress protein HSP70 in vertebrates.
A shift from 28 to 37 degrees C in the incubation temperature of a culture of the platyfish fibroblast cell line, EHS cells (platyfish fibroblast cell line), induced a set of stress proteins. AExpand
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Stress Protein HSP70 in Fish
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Purification and characterization of cathepsin L from the white muscle of chum salmon, Oncorhynchus keta.
1. Cathepsin L of the white muscle of chum salmon (Oncorhynchus keta) in spawning migration was purified to homogeneity by a series of chromatography on DEAE-Sephadex (1st), SP-Sephadex, CM-Sephadex,Expand
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