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Uracil phosphoribosyltransferase

Known as: UMP pyrophosphorylase, UPRTase 
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Standard microarrays measure mRNA abundance, not mRNA synthesis, and therefore cannot identify the mechanisms that regulate gene… Expand
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Highly Cited
2002
Highly Cited
2002
Toxoplasma gondii is a ubiquitous protozoan parasite that is responsible for severe congenital birth defects and fatal… Expand
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Highly Cited
2000
Highly Cited
2000
Transduction of the cytosine deaminase (CD) gene into tumor cells followed by administration of 5-fluorocytosine (5-FC), called 5… Expand
Highly Cited
1998
Highly Cited
1998
5-fluorouracil (5-FU), although a widely used chemotherapeutic agent, has a limited effect in the treatment of human solid tumors… Expand
Highly Cited
1998
Highly Cited
1998
Uracil phosphoribosyltransferase (UPRTase) catalyzes the transfer of a ribosyl phosphate group from α‐D‐5‐phosphoribosyl‐1… Expand
1996
1996
Uracil phosphoribosyltransferase, catalyzing the formation of UMP and pyrophosphate from uracil and 5-phosphoribosyl-alpha-1… Expand
Highly Cited
1995
Highly Cited
1995
  • R. Donald, D. Roos
  • Proceedings of the National Academy of Sciences…
  • 1995
  • Corpus ID: 24668448
Nonhomologous integration vectors have been used to demonstrate the feasibility of insertional mutagenesis in haploid tachyzoites… Expand
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1994
1994
One hundred compounds were evaluated as ligands of Toxoplasma gondii uracil phosphoribosyltransferase (UPRTase, EC 2.4.2.9) by… Expand
Highly Cited
1994
Highly Cited
1994
A 3-kb DNA segment of the Bacillus caldolyticus genome including the 5' end end of the pyr cluster has been cloned and sequenced… Expand
Highly Cited
1992
Highly Cited
1992
The upp gene coding for uracil phosphoribosyltransferase was subcloned on a 5-kb EcoRI restriction fragment along with the purMN… Expand