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Uracil phosphoribosyltransferase

Known as: UMP pyrophosphorylase, UPRTase 
 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Microvesicles (MVs) play an important role in intercellular communication by carrying mRNAs, microRNAs (miRNAs), non-coding RNAs… Expand
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Highly Cited
2009
Highly Cited
2009
We found that the combination of spatially restricted uracil phosphoribosyltransferase (UPRT) expression with 4-thiouracil… Expand
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Highly Cited
2005
Highly Cited
2005
Standard microarrays measure mRNA abundance, not mRNA synthesis, and therefore cannot identify the mechanisms that regulate gene… Expand
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Highly Cited
2002
Highly Cited
2002
Toxoplasma gondii is a ubiquitous protozoan parasite that is responsible for severe congenital birth defects and fatal… Expand
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Highly Cited
2001
Highly Cited
2001
Virus-directed enzyme prodrug therapy (VDEPT) utilising cytosine deaminase (CD) converts 5-fluorocytosine (5-FC) into the… Expand
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Highly Cited
1998
Highly Cited
1998
5-fluorouracil (5-FU), although a widely used chemotherapeutic agent, has a limited effect in the treatment of human solid tumors… Expand
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Highly Cited
1995
Highly Cited
1995
Nonhomologous integration vectors have been used to demonstrate the feasibility of insertional mutagenesis in haploid tachyzoites… Expand
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1994
1994
A 3-kb DNA segment of the Bacillus caldolyticus genome including the 5' end end of the pyr cluster has been cloned and sequenced… Expand
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1994
1994
One hundred compounds were evaluated as ligands of Toxoplasma gondii uracil phosphoribosyltransferase (UPRTase, EC 2.4.2.9) by… Expand
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1992
1992
The upp gene coding for uracil phosphoribosyltransferase was subcloned on a 5-kb EcoRI restriction fragment along with the purMN… Expand
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