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UNC13B protein, human

Known as: Unc13h2 protein, human, UNC-13 Homolog B, Munc13-2 
Protein unc-13 homolog B (1591 aa, ~181 kDa) is encoded by the human UNC13B gene. This protein is involved in exocytosis.
National Institutes of Health

Related topics

Related topics

10 relations
Cellular MembraneExocytosisLigand BindingMolecular Transport

Broader (1)

Nerve Tissue Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Tomosyn guides SNARE complex formation in coordination with Munc18 and Munc13
As a SNARE binding protein, tomosyn has been reported to negatively regulate synaptic exocytosis via arresting syntaxin‐1 and… 
2018
2018
Small molecules that inhibit the late stage of Munc13-4–dependent secretory granule exocytosis in mast cells
Ca2+-dependent secretory granule fusion with the plasma membrane is the final step for the exocytic release of inflammatory… 
2016
2016
Differential Expression of Munc13-2 Produces Unique Synaptic Phenotypes in the Basolateral Amygdala of C57BL/6J and DBA/2J Mice
C57BL/6J (B6) and DBA/2J (D2) mice are well known to differentially express a number of behavioral phenotypes, including anxiety… 
2015
2015
Synaptic-vesicle fusion: a need for speed
  • M. Munson
  • Nature Structural &Molecular Biology
  • 2015
  • Corpus ID: 36059261
Two new studies reveal mechanistic insights into how neurons control the assembly of SNARE complexes and the rapid fusion of… 
2013
2013
Munc13 genotype regulates secretory amyloid precursor protein processing via postsynaptic glutamate receptors
2012
2012
MUNC13-4 Protein Regulates the Oxidative Response and Is Essential for Phagosomal Maturation and Bacterial Killing in Neutrophils*
Background: MUNC13-4 regulates vesicular trafficking, and its deficiency causes immunodeficiency in humans. Results: MUNC13-4… 
Highly Cited
2007
Highly Cited
2007
Interaction Between Munc13-1 and RIM Is Critical for Glucagon-Like Peptide-1–Mediated Rescue of Exocytotic Defects in Munc13-1–Deficient Pancreatic β-Cells
OBJECTIVE—Glucagon-like peptide-1 (GLP-1) rescues insulin secretory deficiency in type 2 diabetes partly via cAMP actions on… 
Highly Cited
2004
Highly Cited
2004
CAST2: identification and characterization of a protein structurally related to the presynaptic cytomatrix protein CAST
The cytomatrix at the active zone (CAZ) is thought to define the site of Ca2+‐dependent exocytosis of neurotransmitters. We have… 
2004
2004
Regulation of syntaxin1A–munc18 complex for SNARE pairing in HEK293 cells
The formation and dissolution of SNARE protein complexes is essential for Ca2+‐triggered fusion of neurotransmitter‐filled… 
Highly Cited
1998
Highly Cited
1998
Cloning and characterization of BAP3 (BAI-associated protein 3), a C2 domain-containing protein that interacts with BAI1.
BAI1 (brain-specific angiogenesis inhibitor 1), a p53-target gene specifically expressed in brain, encodes a seven-span… 
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