UNC13B protein, human

Known as: Unc13h2 protein, human, UNC-13 Homolog B, Munc13-2 
Protein unc-13 homolog B (1591 aa, ~181 kDa) is encoded by the human UNC13B gene. This protein is involved in exocytosis.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2017
024619952017

Papers overview

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Highly Cited
2011
Highly Cited
2011
At a synapse, the presynaptic active zone mediates synaptic vesicle exocytosis. RIM proteins are active zone scaffolding… (More)
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Highly Cited
2008
Highly Cited
2008
Syntaxin/SNAP-25 interactions precede assembly of the ternary SNARE complex that is essential for neurotransmitter release. This… (More)
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Highly Cited
2005
Highly Cited
2005
Munc13 proteins are essential in neurotransmitter release, controlling the priming of synaptic vesicles to a release-ready state… (More)
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Highly Cited
2002
Highly Cited
2002
Synaptic vesicles must be primed to fusion competence before they can fuse with the plasma membrane in response to increased… (More)
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Highly Cited
2002
Highly Cited
2002
Munc13-1 is a presynaptic protein with an essential role in synaptic vesicle priming. It contains a diacylglycerol (DAG)/beta… (More)
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Highly Cited
2000
Highly Cited
2000
In chromaffin cells the number of large dense-core vesicles (LDCVs) which can be released by brief, intense stimuli represents… (More)
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Highly Cited
2000
Highly Cited
2000
Munc13 proteins constitute a family of three highly homologous molecules (Munc13-1, Munc13-2 and Munc13-3). With the exception of… (More)
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Highly Cited
1999
Highly Cited
1999
Neurotransmitter release at synapses between nerve cells is mediated by calcium-triggered exocytotic fusion of synaptic vesicles… (More)
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Highly Cited
1998
Highly Cited
1998
Munc13-1, a mammalian homolog of C. elegans unc-13p, is thought to be involved in the regulation of synaptic transmission. We now… (More)
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Highly Cited
1995
Highly Cited
1995
The unc-13 gene in Caenorhabditis elegans is essential for normal presynaptic function and encodes a large protein with C1- and… (More)
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