Skip to search formSkip to main contentSkip to account menu

UK 68798

Known as: UK-68,798 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

dofetilide

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1995
Highly Cited
1995
Electrophysiologic profile and efficacy of intravenous dofetilide (UK-68,798), a new class III antiarrhythmic drug, in patients with sustained monomorphic ventricular tachycardia. Dofetilide…
1994
1994
Antifibrillatory effects of clofilium in the rabbit isolated heart
1 This study was designed to determine whether clofilium exhibits antifibrillatory activity in a pinacidil + hypoxia‐induced… 
Highly Cited
1993
Highly Cited
1993
Comparative Assessment of Ibutilide, D‐Sotalol, Clofilium, E‐4031, and UK‐68, 798 in a Rabbit Model of Proarrhythmia
Summary Class III agents have been associated with development of a polymorphic ventricular tachycardia (PVT) known as torsades… 
Highly Cited
1993
Highly Cited
1993
Electrophysiological and inotropic effects of H 234/09 (almokalant) in vitro: a comparison with two other novel IK blocking drugs, UK-68,798 (dofetilide) and E-4031.
OBJECTIVE The aim was to compare the electrophysiological and inotropic effects of the novel class III agents H 234/09, UK-68,798… 
1993
1993
Differential Class III and glibenclamide effects on action potential duration in guinea‐pig papillary muscle during normoxia and hypoxia/ischaemia
1 Microelectrode recording techniques were used to study the effects of several potassium channel blockers which are considered… 
1992
1992
Class III Antiarrhythmic Action and Inotropy: Effects of Dofetilide in Acute Ischemic Heart Failure in Dogs
Summary We studied the hemodynamic and metabolic effects of the novel class III antiarrhythmic agent dofetilide (UK-68,798) in… 
1992
1992
Electromechanical Action of Dofetilide and D-Sotalol During Simulated Metabolic Acidosis in Isolated Guinea Pig Ventricular Muscle
Summary: We examined the electromechanical effects of two class III antiarrhythmic agents, dofetilide (UK-68,798) and D-sotalol… 
1992
1992
Effects of altered extracellular potassium and pacing cycle length on the class III antiarrhythmic actions of dofetilide (UK-68,798) in guinea-pig papillary muscle
SummaryThe effects of altered extracellular K+ concentrations ([K+]0) and pacing cycle lengths (CLs) on the electrophysiological… 
1991
1991
Measurement of the class III antidysrhythmic drug, UK-68,798, in plasma by radioimmunoassay.
1991
1991
A dose-ranging study of UK-68,798, a novel class III anti-arrhythmic agent, in normal volunteers.
1. UK-68,798, a novel class III anti-arrhythmic agent was administered intravenously to twelve healthy volunteers in a placebo… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)