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UK 68798

Known as: UK-68,798 
 
National Institutes of Health

Papers overview

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Highly Cited
1995
Highly Cited
1995
There is increasing evidence that class III antiarrhythmic agents may be superior to class I agents for the long-term treatment… Expand
Highly Cited
1993
Highly Cited
1993
Summary Class III agents have been associated with development of a polymorphic ventricular tachycardia (PVT) known as torsades… Expand
Highly Cited
1993
Highly Cited
1993
Class III antiarrhythmic drugs show promise as effective treatments for the suppression of potentially lethal cardiac arrhythmias… Expand
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Highly Cited
1992
Highly Cited
1992
Dofetilide (UK-68,798) is a new class III antiarrhythmic agent. In animal experiments it selectively prolongs the refractory… Expand
Highly Cited
1991
Highly Cited
1991
UK-68,798 increased the duration and effective refractory period of cardiac action potentials recorded in vitro from canine… Expand
Highly Cited
1991
Highly Cited
1991
The effects of cumulative intravenous (i.v.) administration of potent and selective methanesulfonanil-ide class III… Expand
1991
1991
The effects of the new and potent methanesulfonanilide class III antiarrhythmic agents (E-4031, UK-66,914, and UK-68,798) on… Expand
1991
1991
1 The frequency‐dependent electrophysiological effects of UK‐68,798 in concentrations of 1, 3, 10 and 30 nm were examined in… Expand
Highly Cited
1990
Highly Cited
1990
When low doses of clofilium were administered to conscious rabbits, ventricular tachyarrhythmia (VT) with features typical of… Expand
Highly Cited
1990
Highly Cited
1990
The electromechanical effects of UK-68,798 (UK), a novel class III antiarrhythmic drug, were studied in guinea pig and rat… Expand