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UGT1A7 gene

Known as: UDP Glucuronosyltransferase 1 Family, Polypeptide A7 Gene, UGT1G, UDP-GLYCOSYLTRANSFERASE 1 FAMILY, POLYPEPTIDE A7 
This gene plays a role in detoxification.
National Institutes of Health

Related topics

Related topics

4 relations
Metabolic Detoxication, DrugUDP-Glucuronosyltransferase 1-7glycosylation

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UGT1A7 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
In Vitro Comparative Study of the Inhibitory Effects of Mangiferin and Its Aglycone Norathyriol towards UDP-Glucuronosyl Transferase (UGT) Isoforms
Mangiferin (MGF), the predominant constituent of extracts of the mango plant Mangifera Indica L., has been investigated… 
2014
2014
A novel system for predicting the toxicity of irinotecan based on statistical pattern recognition with UGT1A genotypes
To predict precisely severe toxicity of irinotecan, we evaluated the association of UGT1A variants, haplotypes and the… 
2013
2013
UGT1A1*6, 1A7*3, and 1A9*22 genotypes predict severe neutropenia in FOLFIRI‐treated metastatic colorectal cancer in two prospective studies in Japan
Retrospective studies have suggested that UDP‐glucuronosyltransferase (UGT)1A1, UGT1A7, and UGT1A9 predict severe toxicity and… 
2011
2011
Genetic Polymorphisms of UGT1A7 and Cancer Risk: Evidence From 21 Case–Control Studies
The aim of our meta-analysis was to assess the association between UGT1A7 polymorphisms and cancer risk. Case–control studies… 
2010
2010
Polymorphisms in CYP2A13 and UGT1A7 genes and head and neck cancer susceptibility in North Indians.
OBJECTIVES To examine role of genetic variants of CYP2A13 and UGT1A7 genes, involved in activation and detoxification of tobacco… 
2010
2010
Effects of Andrographis paniculata and Orthosiphon stamineus Extracts on the Glucuronidation of 4-Methylumbelliferone in Human UGT Isoforms
The effects of Andrographis paniculata and Orthosiphon stamineus extracts on the in vitro glucuronidation of 4… 
2009
2009
Gilbert's syndrome and hyperbilirubinemia in protease inhibitor therapy--an extended haplotype of genetic variants increases risk in indinavir treatment.
2007
2007
Influence of UGT1A7 and UGT1A9 Intronic I399 Genetic Polymorphisms on Mycophenolic Acid Pharmacokinetics in Japanese Renal Transplant Recipients
Abstract: UGT1A7 and UGT1A9 are uridine diphosphate-glucuronosyltransferase isoforms involved in the glucuronidation of… 
2005
2005
ANALYSIS OF SUBSTRATE SPECIFICITIES AND TISSUE EXPRESSION OF RAT UDP-GLUCURONOSYLTRANSFERASES UGT1A7 AND UGT1A8
The UGT1 complex codes for a subfamily of homologous “1A7-like” UDP-glucuronosyltransferases (UGTs), including UGT1A7 and UGT1A8… 
2004
2004
Gastrointestinally Distributed UDP-glucuronosyltransferase 1A10, Which Metabolizes Estrogens and Nonsteroidal Anti-inflammatory Drugs, Depends upon Phosphorylation*
Among gastrointestinal distributed isozymes encoded at the UGT1 locus, UDP-glucuronosyltransferase 1A10 (UGT1A10) metabolizes a… 
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