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UDP-Glucuronosyltransferase 1-7
Known as:
UDP-Glucuronosyltransferase 1-G
, UGT-1G
, UGT1-07
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UDP-glucuronosyltransferase 1-7 (530 aa, ~60 kDa) is encoded by the human UGT1A7 gene. This protein is involved in the conjugation and elimination of…
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National Institutes of Health
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Related topics
Related topics
13 relations
Carbohydrate Metabolism
Enzyme Gene
Gastric Tissue
Glycosyltransferase Gene
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
In Vitro Comparative Study of the Inhibitory Effects of Mangiferin and Its Aglycone Norathyriol towards UDP-Glucuronosyl Transferase (UGT) Isoforms
Dan Sun
,
Chunze Zhang
,
+7 authors
Z. Fang
Molecules
2017
Corpus ID: 4001966
Mangiferin (MGF), the predominant constituent of extracts of the mango plant Mangifera Indica L., has been investigated…
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2014
2014
Effect of adrenalectomy on expression and induction of UDP-glucuronosyltransferase 1A6 and 1A7 in rats.
Y. Sakakibara
,
M. Katoh
,
Masaya Suzuki
,
Ryoko Kawabe
,
Keisuke Iwase
,
M. Nadai
Biological and Pharmaceutical Bulletin
2014
Corpus ID: 25213893
Uridine 5'-diphosphate (UDP)-glucuronosyltransferase 1A (UGT1A), which catalyzes major phase II reactions, is regulated by…
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2011
2011
Metabolic Pathways of the Camptothecin Analog AR-67
J. Horn
,
M. Milewska
,
S. Arnold
,
M. Leggas
Drug Metabolism And Disposition
2011
Corpus ID: 13957070
7-tert-Butyldimethylsilyl-10-hydroxycamptothecin (AR-67; also known as DB-67) is a novel lipophilic camptothecin analog in early…
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2007
2007
Genetic Polymorphisms in CYP1A1, CYP2D6, UGT1A6, UGT1A7, and SULT1A1 Genes and Correlation with Benzene Exposure in a Chinese Occupational Population
Shou-yong Gu
,
Zhong-bin Zhang
,
Jun-xiang Wan
,
Xi-peng Jin
,
Z. Xia
Journal of Toxicology and Environmental Health…
2007
Corpus ID: 25548219
Metabolic enzymes involved in benzene activation or detoxification, including cytochrome P-450 1A1 (CYP1A1), cytochrome P-450 2D6…
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2006
2006
Activity of rat UGT1A1 towards benzo[a]pyrene phenols and dihydrodiols.
Laura J Webb
,
Kristini K. Miles
,
F. Kessler
,
J. Ritter
Environmental Toxicology and Pharmacology
2006
Corpus ID: 21311211
2005
2005
ANALYSIS OF SUBSTRATE SPECIFICITIES AND TISSUE EXPRESSION OF RAT UDP-GLUCURONOSYLTRANSFERASES UGT1A7 AND UGT1A8
Laura J Webb
,
Kristini K. Miles
,
D. Auyeung
,
F. Kessler
,
J. Ritter
Drug Metabolism And Disposition
2005
Corpus ID: 20450876
The UGT1 complex codes for a subfamily of homologous “1A7-like” UDP-glucuronosyltransferases (UGTs), including UGT1A7 and UGT1A8…
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2004
2004
IDENTIFICATION OF THE RABBIT LIVER UDP-GLUCURONOSYLTRANSFERASE CATALYZING THE GLUCURONIDATION OF 4-ETHOXYPHENYLUREA (DULCIN)
Y. Uesawa
,
A. Staines
,
Audrey C O'Sullivan
,
K. Mohri
,
B. Burchell
Drug Metabolism And Disposition
2004
Corpus ID: 12341049
Dulcin (DL), 4-ethoxyphenylurea, a synthetic chemical about 200 times as sweet as sucrose, has been proposed for use as an…
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2001
2001
Glucuronidation of 1-hydroxypyrene by human liver microsomes and human UDP-glucuronosyltransferases UGT1A6, UGT1A7, and UGT1A9: development of a high-sensitivity glucuronidation assay for human…
L. Luukkanen
,
J. Mikkola
,
T. Forsman
,
P. Taavitsainen
,
J. Taskinen
,
E. Elovaara
Drug Metabolism And Disposition
2001
Corpus ID: 18800743
Human UDP-glucuronosyltransferases (UGT, EC 2.4.1.17) involved in the biotransformation of pyrene were investigated by a…
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Highly Cited
2000
Highly Cited
2000
Distribution and inducibility by 3-methylcholanthrene of family 1 UDP-glucuronosyltransferases in the rat gastrointestinal tract.
Bärbel Grams
,
Andrea Harms
,
S. Braun
,
C. P. Strassburg
,
Michael P. Manns
,
P. Obermayer-Straub
Archives of Biochemistry and Biophysics
2000
Corpus ID: 40498345
UDP-Glucuronosyltransferases (UGT) catalyze the glucuronidation of a broad spectrum of endobiotic and xenobiotic substrates. The…
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Highly Cited
1994
Highly Cited
1994
Glucuronidation of carcinogenic arylamines and their N-hydroxy derivatives by rat and human phenol UDP-glucuronosyltransferase of the UGT1 gene complex.
Achim Orzechowski
,
D. Schrenk
,
B. Bock-Hennig
,
K. Bock
Carcinogenesis
1994
Corpus ID: 25917318
Since carcinogenic arylamines are sequentially oxidized and conjugated with glucuronic acid, differences in glucuronidation may…
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