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UDP-Glucuronosyltransferase 1-7

Known as: UDP-Glucuronosyltransferase 1-G, UGT-1G, UGT1-07 
UDP-glucuronosyltransferase 1-7 (530 aa, ~60 kDa) is encoded by the human UGT1A7 gene. This protein is involved in the conjugation and elimination of… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND & AIMS Coffee is one of the most widely consumed beverages worldwide. Epidemiologic data indicate that coffee… Expand
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Highly Cited
2010
Highly Cited
2010
Phase II metabolism by UDP-glucuronosyltransferases (UGTs) and sulfotransferases (SULTs) is the predominant metabolic pathway… Expand
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Highly Cited
2005
Highly Cited
2005
UDP-glucuronosyltransferase (UGT) enzymes catalyze the glucuronidation reaction, which is a major pathway in the catabolism and… Expand
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Review
2004
Review
2004
The UDP glucuronosyltransferases (UGT) of the gastrointestinal (GI) tract have a crucial role in protection against the toxic… Expand
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Highly Cited
2003
Highly Cited
2003
In vitro metabolic studies revealed that along with UDP-glucuronosyltransferase (UGT) 1A1, the hepatic UGT1A9 and the… Expand
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Highly Cited
2000
Highly Cited
2000
One of the most important mechanisms involved in host defense against xenobiotic chemicals and endogenous toxins is the… Expand
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Highly Cited
2000
Highly Cited
2000
UDP-Glucuronosyltransferases (UGT) catalyze the glucuronidation of a broad spectrum of endobiotic and xenobiotic substrates. The… Expand
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Highly Cited
1999
Highly Cited
1999
7-Ethyl-10-hydroxycamptothecin (SN-38) is a very promising anticancer drug used for the treatment of metastatic colonrectal… Expand
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Highly Cited
1997
Highly Cited
1997
Family 1 UDP-glucuronosyltransferases (UGTs) (UGT1A) are encoded by a locus that predicts the existence of at least nine… Expand
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Highly Cited
1994
Highly Cited
1994
Since carcinogenic arylamines are sequentially oxidized and conjugated with glucuronic acid, differences in glucuronidation may… Expand
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