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UDP-glucuronosyltransferase, UGT2B28

Known as: UGT2B28 
 
National Institutes of Health

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2 relations

Broader (1)

Glucuronosyltransferase
UGT2B28 gene

Papers overview

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2017
2017
UDP-glucuronosyltransferases and biochemical recurrence in prostate cancer progression
BackgroundUridine 5′-diphosphate-glucuronosyltransferase 2B (UGT2B) genes code for enzymes that catalyze the clearance of… Expand
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2017
2017
Overexpression of lipid metabolism genes and PBX1 in the contralateral breasts of women with estrogen receptor‐negative breast cancer
Risk biomarkers for estrogen receptor (ER)-negative breast cancer have clear value for breast cancer prevention. We previously… Expand
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2016
2016
Epigenetic regulation of steroid inactivating UDP-glucuronosyltransferases by microRNAs in prostate cancer
Androgens play a central role in prostate cancer progression. Systemic and local androgen bioavailability is controlled by UDP… Expand
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2016
2016
Perspective on the regulatory role of UGT2B28 as a conjugating enzyme in the progression of prostate cancer
The maintenance of steroid homeostasis in the prostate is critical, with perturbation of steroidogenesis contributing to the… Expand
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2015
2015
Germline copy number loss of UGT2B28 and gain of PLEC contribute to increased human esophageal squamous cell carcinoma risk in Southwest China.
Esophageal squamous cell carcinoma (ESCC) is one of the most common cancers worldwide with poor prognosis. Thus, identification… Expand
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2013
2013
The effect of copy number variation in the phase II detoxification genes UGT2B17 and UGT2B28 on colorectal cancer risk.
BACKGROUND Genetic polymorphisms in combination with the Western-style diet, physical inactivity, smoking, excessive alcohol… Expand
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2011
2011
Gene copy number variations: it is important to determine which allele is affected.
Copy number variations (CNVs) are one of the primary sources of variation found in the human genome. They involve both the… Expand
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2011
2011
Quantitative analysis of UGT2B28 mRNA expression by real-time RT-PCR and application to human tissue distribution study.
We recently established a method for quantitative determination of human catalytically active UDP-glucuronosyltransferases (UGTs… Expand
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2009
2009
Copy-number variations (CNVs) of the human sex steroid metabolizing genes UGT2B17 and UGT2B28 and their associations with a UGT2B15 functional polymorphism.
UGT2B17 and UGT2B28 are among the most commonly deleted genes in humans and encode members of the uridine diphosphate (UDP… Expand
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Highly Cited
2001
Highly Cited
2001
Isolation and characterization of the UGT2B28 cDNA encoding a novel human steroid conjugating UDP-glucuronosyltransferase.
UDP-glucuronosyltransferase (UGT) enzymes belonging to the UGT2B subfamily catalyze the transfer of glucuronic acid to a large… Expand
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