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UD CG 115

Known as: UD-CG 115, UD-CG115 
National Institutes of Health

Related topics

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1 relation

Broader (1)

pimobendan

Papers overview

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2001
2001
Decrease in Ca(2+)-sensitizing effect of UD-CG 212 Cl, a metabolite of pimobendan, under acidotic condition in canine ventricular myocardium.
We studied the influence of acidosis on the positive inotropic effect of UD-CG 212 Cl (4,5-dihydro-6-[2-(4-hydroxyphenyl)-1H… 
1997
1997
Contribution of phosphodiesterase isozymes to the regulation of the L‐type calcium current in human cardiac myocytes
1 To determine the contribution of the various phosphodiesterase (PDE) isozymes to the regulation of the L‐type calcium current… 
1995
1995
Low concentrations of UD-CG 212 enhance myocyte contractility by an increase in calcium responsiveness in the presence of inorganic phosphate
Recent data show that UD-CG 212 in nanomolar concentrations increases myofibrillar Ca++ responsiveness of chemically skinned… 
1992
1992
Electrophysiological actions of the pimobendan metabolite, UD-CG 212 Cl, in guinea pig myocardium.
Pimobendan (UD-CG 115 BS), an inotropic agent and inhibitor of type III phosphodiesterase activity, is demethylated in vivo to… 
1992
1992
抗心不全薬UD-CG115 BSカプセル(Pimobendan)の臨床薬理学的検討
1991
1991
Different Mechanisms Involved in the Positive Inotropic Effects of Benzimidazole Derivative UD‐CG 115 BS (Pimobendan) and Its Demethylated Metabolite UD‐CG 212 Cl in Canine Ventricular Myocardium
UD-CG 115 BS produced a positive inotropic effect in a concentration-dependent manner (EC50 – 9.2 × 10 -5 M, efficacy = 0.65) in… 
1989
1989
Acute Effects of Intraveneous UD‐CG 115 BS (Pimobendan) on the Cardiovascular System and Left Ventricular Pump Function
Acute hemodynamic effects of 5 and 10 nig i.v. UD-CG 115 BS (pimobendan) were studied by right and left heart catheterization in… 
1989
1989
Clinical Efficacy of Pimobendan (UD‐CG 115 BS) in Patients with Chronic Congestive Heart Failure
The pyridazoline derivative UD-CG 115 BS (pimobendan) is a noneatecholamine. nonglyeoside new inotropic compound with potent… 
1989
1989
Platelet aggregation inhibitory effects of the new positive inotropic agents pimobendan and UD CG 212 in whole blood.
A method is described for studying platelet function in human whole blood immediately after venepuncture in order to evaluate the… 
1984
1984
UD-CG 115 — a cardiotonic pyridazinone which elevates cyclic AMP and prolongs the action potential in guinea-pig papillary muscle
Summary1.The mechanism of the positive inotropic effect of a benzimidazole-pyridazinone, UD-CG 115, was analysed in the isolated… 
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