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UD CG 115

Known as: UD-CG 115, UD-CG115 
National Institutes of Health

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pimobendan

Papers overview

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1997
1997
Effects of pimobendan and its active metabolite, UD-CG 212 Cl, on Ca2+-activated K+ channels in vascular smooth-muscle cells.
The aim of this study was to clarify the mechanisms of activation of Ca2+-dependent K+ (K(Ca)) channels by pimobendan, a new… 
1997
1997
Reversal of phosphate induced decreases in force by the benzimidazole pyridazinone, UD-CG 212 CL, in myofilaments from human ventricle
UD-CG 212 Cl, (Fig. 1: 4,5-dihydro-6-[2-(4-hydroxyphenyl)-1H-benzimidazole-5-yl]-5-methyl-3(2H)-pyrid azinone), is the primary… 
1995
1995
Low concentrations of UD-CG 212 enhance myocyte contractility by an increase in calcium responsiveness in the presence of inorganic phosphate
Recent data show that UD-CG 212 in nanomolar concentrations increases myofibrillar Ca++ responsiveness of chemically skinned… 
1992
1992
抗心不全薬UD-CG115 BSカプセル(Pimobendan)の臨床薬理学的検討
1990
1990
Antagonism of novel inotropic agents at A1 adenosine receptors and m-cholinoceptors in human myocardium
SummaryThe effects of the new inotropic agents saterinone, sulmazole, UD-CG 212.C1 and milrinone at A1 adenosine receptors and m… 
1989
1989
Acute Effects of Intraveneous UD‐CG 115 BS (Pimobendan) on the Cardiovascular System and Left Ventricular Pump Function
Acute hemodynamic effects of 5 and 10 nig i.v. UD-CG 115 BS (pimobendan) were studied by right and left heart catheterization in… 
1989
1989
Influence of the Positive Inotropic Substance Pimobendan (UD‐CG 115 BS) on Contractile Economy of Guinea Pig Papillary μscles
Using antimony-bisμth myothermal equipment, we measured siμltaneously the initial heat liberated from and the stress-time… 
1984
1984
UD-CG 115 — a cardiotonic pyridazinone which elevates cyclic AMP and prolongs the action potential in guinea-pig papillary muscle
Summary1.The mechanism of the positive inotropic effect of a benzimidazole-pyridazinone, UD-CG 115, was analysed in the isolated… 
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