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UBE4B gene

Known as: KIAA0684, UFD2A, UBE4B 
This gene plays a role in polyubiquitination.
National Institutes of Health

Related topics

Related topics

6 relations
ApoptosisPolyubiquitinationUBE4A geneUbe4b protein, mouse

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Expression and prognostic role of ubiquitination factor E4B in primary hepatocellular carcinoma
Ubiquitination factor E4B (UBE4B) has been speculated to have contradictory functions upon tumorigenesis as an oncogene or tumor… 
2015
2015
UBE4B targets phosphorylated p53 at serines 15 and 392 for degradation
Phosphorylation of p53 is a key mechanism responsible for the activation of its tumor suppressor functions in response to various… 
2015
2015
Correction: Regulation of p53 Level by UBE4B in Breast Cancer
open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use… 
2012
2012
Growth factor receptor trafficking as a potential therapeutic target in pediatric cancer
Growth factor receptors (GFRs) are often aberrantly expressed in tumor cells, and altered GFR expression and activity contribute… 
2011
2011
A Novel Conserved Isoform of the Ubiquitin Ligase UFD2a/UBE4B Is Expressed Exclusively in Mature Striated Muscle Cells
Yeast Ufd2p was the first identified E4 multiubiquitin chain assembly factor. Its vertebrate homologues later referred to as… 
2011
2011
Ubiquitin Ligase Ufd2 Is Required for Efficient Degradation of Mps1 Kinase
Background: Ufd2 is a U-box-containing ubiquitin-protein ligase. Results: Mps1 turnover is regulated by Ufd2 in yeast and… 
2010
2010
An animal model manifesting neurodegeneration and obesity
Although the existence of a link between neurodegenerative diseases and obesity has been suggested, a causal relation between… 
2006
2006
The two human homologues of yeast UFD2 ubiquitination factor, UBE4A and UBE4B, are located in common neuroblastoma deletion regions and are subject to mutations in tumours.
Highly Cited
2003
Highly Cited
2003
Characterization of the mouse gene for the U-box-type ubiquitin ligase UFD2a.
Review
2003
Review
2003
[Mechanisms to control degradation of polyglutamine-containing protein].
Machado-Joseph disease (MJD)/Spinocerebellar ataxia type 3 (SCA3) is neurodegenerative disease which is caused by polyglutamine… 
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