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Ubiquitin ligases: cell-cycle control and cancer
- K. Nakayama, K. Nakayama
- BiologyNature Reviews Cancer
- 1 May 2006
TLDR
Two E3 ubiquitin ligases, SCF‐Skp2 and DDB1‐Cul4, target human Cdt1 for proteolysis
- H. Nishitani, Nozomi Sugimoto, T. Nishimoto
- BiologyThe EMBO journal
- 8 March 2006
TLDR
Phosphorylation‐dependent degradation of c‐Myc is mediated by the F‐box protein Fbw7
- M. Yada, S. Hatakeyama, K. Nakayama
- BiologyThe EMBO journal
- 19 May 2004
TLDR
VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.
- T. Kamura, K. Maenaka, K. Nakayama
- BiologyGenes & development
- 15 December 2004
TLDR
CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity.
- Y. Imai, Mariko Soda, R. Takahashi
- Biology, ChemistryMolecular cell
- 1 July 2002
Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase stabilizes beta-catenin through inhibition of its ubiquitination.
- S. Hino, C. Tanji, K. Nakayama, A. Kikuchi
- Biology, ChemistryMolecular and cellular biology
- 2005
TLDR
Mice Lacking p27 Kip1 Display Increased Body Size, Multiple Organ Hyperplasia, Retinal Dysplasia, and Pituitary Tumors
- K. Nakayama, N. Ishida, K. Nakayama
- Biology, MedicineCell
- 31 May 1996
Blue light-induced autophosphorylation of phototropin is a primary step for signaling
- Shin-Ichiro Inoue, T. Kinoshita, M. Matsumoto, K. Nakayama, M. Doi, K. Shimazaki
- Biology, ChemistryProceedings of the National Academy of Sciences
- 8 April 2008
Phototropins are autophosphorylating protein kinases of plant-specific blue light receptors. They regulate various blue light responses, including phototropism, chloroplast movements, hypocotyl…
Essential role for ZAP-70 in both positive and negative selection of thymocytes
- I. Negishi, N. Motoyama, D. Loh
- BiologyNature
- 3 August 1995
TLDR
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