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UBE2N protein, human

Known as: Epididymis Secretory Protein Li 71, Bendless-Like Ubiquitin Conjugating Enzyme, ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast), human 
Ubiquitin-conjugating enzyme E2 N (152 aa, ~17 kDa) is encoded by the human UBE2N gene. This protein plays a role in the polyubiquitination of… 
National Institutes of Health

Related topics

Related topics

10 relations
Cell NucleusCytoplasmDNA RepairEnzyme Gene

Broader (1)

Ubiquitin-Conjugating Enzymes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Arabidopsis UBC13 differentially regulates two programmed cell death pathways in responses to pathogen and low-temperature stress.
UBC13 is required for Lys63-linked polyubiquitination and innate immune responses in mammals, but its functions in plant immunity… 
2015
2015
Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Ubc13 is an E2 ubiquitin conjugating enzyme that functions in nuclear DNA damage signaling and cytoplasmic NF-κB signaling. Here… 
Review
2011
Review
2011
RNF8-dependent histone ubiquitination during DNA damage response and spermatogenesis.
Histone ubiquitination regulates the chromatin structure that is important for many biological processes. Recently… 
2009
2009
The ubiquitin ligase Triad1 inhibits myelopoiesis through UbcH7 and Ubc13 interacting domains
Ubiquitination plays a major role in many aspects of hematopoiesis. Alterations in ubiquitination have been implicated in… 
Highly Cited
2008
Highly Cited
2008
Arabidopsis UEV1D Promotes Lysine-63–Linked Polyubiquitination and Is Involved in DNA Damage Response[W]
DNA damage tolerance (DDT) in budding yeast requires Lys-63–linked polyubiquitination of the proliferating cell nuclear antigen… 
Highly Cited
2005
Highly Cited
2005
ISG15 modification of Ubc13 suppresses its ubiquitin-conjugating activity.
Highly Cited
2005
Highly Cited
2005
A Single Mms2 “Key” Residue Insertion into a Ubc13 Pocket Determines the Interface Specificity of a Human Lys63 Ubiquitin Conjugation Complex*
Human Ubc13 and Mms2 (or its homolog, Uev1) form a unique ubiquitin-conjugating enzyme (Ubc) complex that generates atypical… 
Highly Cited
2003
Highly Cited
2003
RNF5, a RING Finger Protein That Regulates Cell Motility by Targeting Paxillin Ubiquitination and Altered Localization
ABSTRACT RNF5 is a RING finger protein found to be important in the growth and development of Caenorhabditis elegans. The search… 
Highly Cited
2001
Highly Cited
2001
Molecular Insights into Polyubiquitin Chain Assembly Crystal Structure of the Mms2/Ubc13 Heterodimer
Highly Cited
1984
Highly Cited
1984
Upper critical magnetic field of the heavy-fermion superconductor UBe13.
The longitudinal and transverse upper critical magnetic fields H/sub c/2/sup parallel/ and H/sub c/2/sup perpendicular/ as a… 
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