Ubiquitin-Conjugating Enzymes

Known as: Enzyme E2, Ubiquitin-Conjugating, Ubiquitin-Conjugating Enzymes [Chemical/Ingredient], Ubiquitin Conjugating Enzyme E2 
A class of enzymes that form a thioester bond to UBIQUITIN with the assistance of UBIQUITIN-ACTIVATING ENZYMES. They transfer ubiquitin to the LYSINE… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
05101519902018

Related topics

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34 relations

Narrower (21)

Birc6 protein, ratCDC34 protein, S cerevisiaeMms2 protein, S pombeUBE2C protein, human
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In BloodProcess of secretionUBE2F geneUBE2M gene
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Related mentions per year

Related mentions per year

1936-2019
19401960198020002020
Ubiquitin-Conjugating Enzymes
standards characteristics
physiological aspects
ubiquitin-protein ligase
chemical synthesis
UBE2S gene

Papers overview

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2013
2013
E2 ubiquitin conjugating enzymes regulate the deubiquitinating activity of OTUB1
OTUB1 is a Lys48-specific deubiquitinating enzyme that forms a complex in vivo with E2 ubiquitin (Ub)-conjugating enzymes… (More)
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2008
2008
Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes
Ubiquitin (E3) ligases interact with specific ubiquitin conjugating (E2) enzymes to ubiquitinate particular substrate proteins… (More)
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Highly Cited
2004
Highly Cited
2004
Arabidopsis COP10 forms a complex with DDB1 and DET1 in vivo and enhances the activity of ubiquitin conjugating enzymes.
COP10 is a ubiquitin-conjugating enzyme variant (UEV), which is thought to act together with COP1, DET1, and the COP9 signalosome… (More)
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2003
2003
Pex10p links the ubiquitin conjugating enzyme Pex4p to the protein import machinery of the peroxisome.
The protein import machinery of the peroxisome consists of many proteins, collectively called the peroxins. By applying the split… (More)
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2002
2002
Control of ubiquitination of proteins in rat tissues by ubiquitin conjugating enzymes and isopeptidases.
The activity of the ubiquitin-dependent proteolytic system in differentiated tissues under basal conditions remains poorly… (More)
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2001
2001
Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2–hUbc13
The ubiquitin conjugating enzyme complex Mms2–Ubc13 plays a key role in post-replicative DNA repair in yeast and the NF-κB signal… (More)
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1995
1995
Identification of a family of closely related human ubiquitin conjugating enzymes.
Two very closely related human E2 ubiquitin conjugating enzymes, UbfH5B and UbcH5C, have been identified. These enzymes are… (More)
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1995
1995
The Schizosaccharomyces pombe hus5 gene encodes a ubiquitin conjugating enzyme required for normal mitosis.
Normal eukaryotic cells do not enter mitosis unless DNA is fully replicated and repaired. Controls called 'checkpoints', mediate… (More)
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Highly Cited
1992
Highly Cited
1992
Structure of a diubiquitin conjugate and a model for interaction with ubiquitin conjugating enzyme (E2).
Covalent ligation of multiubiquitin chains targets eukaryotic proteins for degradation. In such multiubiquitin chains, successive… (More)
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1991
1991
Yeast RAD6 encoded ubiquitin conjugating enzyme mediates protein degradation dependent on the N-end-recognizing E3 enzyme.
The RAD6 gene of Saccharomyces cerevisiae encodes a 20 kd ubiquitin conjugating (E2) enzyme that is required for DNA repair, DNA… (More)
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