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UBE2N gene

Known as: ubiquitin conjugating enzyme E2 N, MGC8489, UBIQUITIN-CONJUGATING ENZYME E2N 
This gene plays a role in polyubiquitination.
National Institutes of Health

Related topics

Related topics

6 relations
DNA RepairPolyubiquitinationSignal Transduction InductionUBE2N protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Legionella pneumophila inhibits immune signaling via MavC-mediated transglutaminase-induced ubiquitination of UBE2N
The bacterial pathogen Legionella pneumophila modulates host immunity using effectors translocated by its Dot/Icm transporter to… 
2018
2018
Discovery of Ubiquitin Deamidases in the Pathogenic Arsenal of Legionella pneumophila.
Highly Cited
2017
Highly Cited
2017
Ube2D3 and Ube2N are essential for RIG-I-mediated MAVS aggregation in antiviral innate immunity
Innate immunity plays a pivotal role in virus infection. RIG-I senses viral RNA and initiates an effective innate immune response… 
Highly Cited
2015
Highly Cited
2015
Proteomics analysis of malignant and benign prostate tissue by 2D DIGE/MS reveals new insights into proteins involved in prostate cancer
The key to a more effective diagnosis, prognosis, and therapeutic management of prostate cancer (PCa) could lie in the direct… 
Highly Cited
2014
Highly Cited
2014
Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis
The protein kinase PINK1 was recently shown to phosphorylate ubiquitin (Ub) on Ser65, and phosphoUb activates the E3 ligase… 
Highly Cited
2014
Highly Cited
2014
The ubiquitin-conjugating enzymes UBE2N, UBE2L3 and UBE2D2/3 are essential for Parkin-dependent mitophagy
ABSTRACT Depolarized mitochondria are degraded by mitophagy in a process that depends on the Parkinson's disease gene products… 
Highly Cited
2014
Highly Cited
2014
RNF168-mediated H2A neddylation antagonizes ubiquitylation of H2A and regulates DNA damage repair
ABSTRACT NEDD8 is an important regulatory factor in many biological processes. However, the substrates for neddylation, and the… 
2014
2014
The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines
Unlike the other MAP3Ks, MEKK1 (encoded by Map3k1) contains a PHD motif. To understand the role of this motif, we have created a… 
Highly Cited
2007
Highly Cited
2007
Arabidopsis HY5 protein functions as a DNA‐binding tag for purification and functional immobilization of proteins on agarose/DNA microplate
1998
1998
A Fifteen-Amino-Acid Peptide Inhibits Human Papillomavirus E1-E2 Interaction and Human Papillomavirus DNA Replication In Vitro
ABSTRACT Mutation of the conserved glutamic acid residue at position 39 of human papillomavirus type 16 (HPV-16) E2 to alanine… 
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