UBC gene

Known as: Ubiquitin C Gene, polyubiquitin-C, POLYUBIQUITIN 
This gene plays a role in ubiquitin-dependent proteolysis.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1988-2017
010203019882017

Papers overview

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Highly Cited
2009
Highly Cited
2009
Small RNAs targeted to gene promoters in human cells can mediate transcriptional gene silencing (TGS) by directing silent state… (More)
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Highly Cited
2009
Highly Cited
2009
Linkage-specific polyubiquitin recognition is thought to make possible the diverse set of functional outcomes associated with… (More)
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Highly Cited
2009
Highly Cited
2009
Recruitment of substrates to the 26S proteasome usually requires covalent attachment of the Lys48-linked polyubiquitin chain. In… (More)
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Highly Cited
2008
Highly Cited
2008
Posttranslational modification of proteins with polyubiquitin occurs in diverse signaling pathways and is tightly regulated to… (More)
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Highly Cited
2008
Highly Cited
2008
AMPK (AMP-activated protein kinase)-related kinases regulate cell polarity as well as proliferation and are activated by the LKB1… (More)
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Highly Cited
2006
Highly Cited
2006
The ubiquitin system plays important roles in the regulation of numerous cellular processes by conjugating ubiquitin to target… (More)
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Highly Cited
2005
Highly Cited
2005
Rip1 is required for IkappaB kinase activation in response to tumor necrosis factor alpha (TNF-alpha) and has been implicated in… (More)
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Highly Cited
2004
Highly Cited
2004
The breast and ovarian cancer suppressor BRCA1 acquires significant ubiquitin ligase activity when bound to BARD1 as a RING… (More)
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Highly Cited
2003
Highly Cited
2003
The BRCA1 tumor suppressor forms a heterodimer with the BARD1 protein, and the resulting complex functions as an E3 ubiquitin… (More)
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Highly Cited
2002
Highly Cited
2002
The 26S proteasome is the chief site of regulatory protein turnover in eukaryotic cells. It comprises one 20S catalytic complex… (More)
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