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U 69593

Known as: Benzeneacetamide, N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspiro(4.5)dec-8-yl)-, (5alpha,7alpha,8beta)-(-)-, U-69593 
 
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Opioid receptors display basal signaling (constitutive, agonist-independent activity), which seems to be regulated by agonist… Expand
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Highly Cited
2003
Highly Cited
2003
We showed previously that cAMP response element-binding protein (CREB) within the nucleus accumbens (NAc) of rats regulates… Expand
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Highly Cited
2003
Highly Cited
2003
RationaleElevations in cAMP response element binding protein (CREB) function within the mesolimbic system of rats reduce cocaine… Expand
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Highly Cited
2000
Highly Cited
2000
Coadministration of κ-opioid receptor agonists (κ-agonists) with cocaine prevents alterations in dialysate dopamine (DA… Expand
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Highly Cited
1999
Highly Cited
1999
Abstract : The effect of a k‐opioid receptor agonist on acute amphetamine‐induced behavioral activation and dialysate levels of… Expand
1998
1998
U‐69593, the selective κ‐opioid agonist, was repeatedly administered in single daily injections (0.32 mg/kg) to male, Sprague… Expand
Highly Cited
1995
Highly Cited
1995
Xenopus oocytes expressed kappa-opioid specific binding sites after injection of cRNA prepared from a clone of the rat kappa… Expand
Highly Cited
1994
Highly Cited
1994
Repeated intermittent administration of cocaine (20 mg kg-1, i.p.) for 3 days dramatically increased basal dopamine (DA) overflow… Expand
Highly Cited
1993
Highly Cited
1993
Both the reinforcing and aversive effects of exogenous opioids have been attributed to the activation of opioid receptors within… Expand
Highly Cited
1993
Highly Cited
1993
The effects of treatment with the selective kappa-opioid receptor agonist U-69593 upon cocaine-induced changes in locomotor… Expand